Literature DB >> 15542007

Deep brain stimulation of the subthalamic nucleus reduces antiparkinsonian medication costs.

P David Charles1, Bimal B Padaliya, William J Newman, Chandler E Gill, Cassondra D Covington, John Y Fang, Stephanie A So, Michael G Tramontana, Peter E Konrad, Thomas L Davis.   

Abstract

This study reports a retrospective analysis of 16 patients to determine changes in medication costs associated with deep brain stimulation of the bilateral subthalamic nucleus (DBS B-STN). Antiparkinsonian medication (APMED) costs were evaluated pre- and post-operatively at 1 and 2 years, based on prescribed dosages. After treatment with DBS, patients experienced a 32% reduction in APMED costs after 1 year and a 39% reduction after 2 years. Hypothetical projections of total potential savings are presented, accounting for increasingly complex medication regimens and medication cost inflation. DBS patients may experience a significant long-term reduction in the cost of their pharmacologic treatment.

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Year:  2004        PMID: 15542007     DOI: 10.1016/j.parkreldis.2004.05.006

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN: 1353-8020            Impact factor:   4.891


  12 in total

1.  Depression and intelligence in patients with Parkinson's disease and deep-brain stimulation.

Authors:  Courtney R Schadt; Katie L Cox; Michael G Tramontana; Daniel W Byrne; Thomas L Davis; John Y Fang; Peter E Konrad; Bhavna Padaliya; Robert W Mutter; Chandler E Gill; Caralee R Richardson; P David Charles
Journal:  J Natl Med Assoc       Date:  2006-07       Impact factor: 1.798

Review 2.  A review of the health-related quality of life and economic impact of Parkinson's disease.

Authors:  Clare H Dowding; Claire L Shenton; Sam S Salek
Journal:  Drugs Aging       Date:  2006       Impact factor: 3.923

3.  Longitudinal medication profile and cost savings in Parkinson's disease patients after bilateral subthalamic nucleus deep brain stimulation.

Authors:  Jing Han Ng; Angela An Qi See; Zheyu Xu; Nicolas Kon Kam King
Journal:  J Neurol       Date:  2020-05-04       Impact factor: 4.849

4.  Deep brain stimulation in early Parkinson's disease: enrollment experience from a pilot trial.

Authors:  P D Charles; R M Dolhun; C E Gill; T L Davis; M J Bliton; M G Tramontana; R M Salomon; L Wang; P Hedera; F T Phibbs; J S Neimat; P E Konrad
Journal:  Parkinsonism Relat Disord       Date:  2011-11-21       Impact factor: 4.891

5.  The health-related, social, and economic consequences of parkinsonism: a controlled national study.

Authors:  Poul Jennum; Marielle Zoetmulder; Lise Korbo; Jakob Kjellberg
Journal:  J Neurol       Date:  2011-03-11       Impact factor: 4.849

6.  Early subthalamic nucleus deep brain stimulation in Parkinson's disease reduces long-term medication costs.

Authors:  Mallory Hacker; Grace Cannard; Maxim Turchan; Jacqueline Meystedt; Thomas Davis; Fenna Phibbs; Peter Hedera; Peter Konrad; David Charles
Journal:  Clin Neurol Neurosurg       Date:  2021-10-08       Impact factor: 1.876

7.  Deep Brain Stimulation in Early-Stage Parkinson's Disease: Patient Experience after 11 Years.

Authors:  Kaitlyn Stoehr; Kian Pazira; Kemberlee Bonnet; David Schlundt; David Charles; Mallory Hacker
Journal:  Brain Sci       Date:  2022-06-11

8.  Deep brain stimulation for Parkinson's disease and other movement disorders: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2005-03-01

9.  Pilot study assessing the feasibility of applying bilateral subthalamic nucleus deep brain stimulation in very early stage Parkinson's disease: study design and rationale.

Authors:  David Charles; Christopher Tolleson; Thomas L Davis; Chandler E Gill; Anna L Molinari; Mark J Bliton; Michael G Tramontana; Ronald M Salomon; Chris Kao; Lily Wang; Peter Hedera; Fenna T Phibbs; Joseph S Neimat; Peter E Konrad
Journal:  J Parkinsons Dis       Date:  2012       Impact factor: 5.568

10.  Deep brain stimulation for early-stage Parkinson's disease: an illustrative case.

Authors:  Chandler E Gill; Laura A Allen; Peter E Konrad; Thomas L Davis; Mark J Bliton; Stuart G Finder; Michael G Tramontana; C Chris Kao; Michael S Remple; Courtney H Bradenham; P David Charles
Journal:  Neuromodulation       Date:  2011-09-21
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