Literature DB >> 15541661

Molecular basis of intervertebral disc degeneration.

Matthew H Walker1, D Greg Anderson.   

Abstract

This review will acquaint the reader with normal development, structure, and function of the intervertebral disc. The disc is composed of the vertebral endplate, nucleus pulposus, and annulus fibrosus. These three functional components all serve important purposes for health and function of the disc. Nutrition and biomechanics are also discussed. The molecular basis of disc degeneration is reviewed so that biologic approaches to the reversal and or treatment of disc degeneration may be better understood.

Entities:  

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Year:  2004        PMID： 15541661     DOI： 10.1016/j.spinee.2004.07.010

Source DB:  PubMed          Journal:  Spine J        ISSN： 1529-9430            Impact factor:   4.166


  38 in total

1.  Microcarrier bioreactor culture system promotes propagation of human intervertebral disc cells.

Authors:  L Zhang; B Ning; T Jia; W Gong; M Cong; J-F Chen; S-Y Yang
Journal:  Ir J Med Sci       Date:  2010-08-17       Impact factor: 1.568

2.  Injectable hydrogel provides growth-permissive environment for human nucleus pulposus cells.

Authors:  Priyanka Priyadarshani; Yongchao Li; ShangYou Yang; Li Yao
Journal:  J Biomed Mater Res A       Date:  2015-10-15       Impact factor: 4.396

Review 3.  Regeneration of intervertebral disc by mesenchymal stem cells: potentials, limitations, and future direction.

Authors:  Victor Y L Leung; Danny Chan; Kenneth M C Cheung
Journal:  Eur Spine J       Date:  2006-07-15       Impact factor: 3.134

Review 4.  [Imaging in rheumatology. Degenerative diseases of the spine].

Authors:  J Steinhagen; C R Habermann; J P Petersen; R Kothe; W Rüther
Journal:  Z Rheumatol       Date:  2006-12       Impact factor: 1.372

5.  The fabrication of cryogel scaffolds incorporated with poloxamer 407 for potential use in the regeneration of the nucleus pulposus.

Authors:  Nicholas A Temofeew; Katherine R Hixon; Sarah H McBride-Gagyi; Scott A Sell
Journal:  J Mater Sci Mater Med       Date:  2017-01-31       Impact factor: 3.896

Review 6.  Scaffolding in tissue engineering: general approaches and tissue-specific considerations.

Authors:  B P Chan; K W Leong
Journal:  Eur Spine J       Date:  2008-11-13       Impact factor: 3.134

7.  Translation of an injectable triple-interpenetrating-network hydrogel for intervertebral disc regeneration in a goat model.

Authors:  Sarah E Gullbrand; Thomas P Schaer; Prateek Agarwal; Justin R Bendigo; George R Dodge; Weiliam Chen; Dawn M Elliott; Robert L Mauck; Neil R Malhotra; Lachlan J Smith
Journal:  Acta Biomater       Date:  2017-07-19       Impact factor: 8.947

8.  Multiscale and multimodal structure-function analysis of intervertebral disc degeneration in a rabbit model.

Authors:  B G Ashinsky; S E Gullbrand; E D Bonnevie; S A Mandalapu; C Wang; D M Elliott; L Han; R L Mauck; H E Smith
Journal:  Osteoarthritis Cartilage       Date:  2019-08-13       Impact factor: 6.576

9.  The Relation Between Sox9, TGF-beta1, and Proteoglycan in Human Intervertebral Disc Cells.

Authors:  Yong-Jik Lee; Min-Ho Kong; Kwan-Young Song; Kye-Heui Lee; Su-Hak Heo
Journal:  J Korean Neurosurg Soc       Date:  2008-03-20

10.  A comparison of the type IX collagen levels of the intervertebral disc materials in diabetic and non-diabetic patients who treated with lumbar microdiscectomy.

Authors:  Metin Kaplan; Lutfu Arici; Sait Ozturk; Bengu Cobanoglu Simsek; Omer Batu Hergunsel; Fatih Serhat Erol
Journal:  Eur Spine J       Date:  2017-10-25       Impact factor: 3.134
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