| Literature DB >> 15541513 |
Florian Raible1, Michael Brand.
Abstract
The midbrain-hindbrain organizer (MHO) is a signalling centre that orchestrates development of the mesencephalic and anterior metencephalic primordia. In recent years, details have been revealed about the molecular nature of these signals, their transmission and reception, and the regulatory processes associated with MHO function. This article reviews recent progress in understanding the genetic and molecular components of the MHO, and how they synergize to control brain development.Entities:
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Year: 2004 PMID： 15541513 DOI： 10.1016/j.tins.2004.10.003
Source DB: PubMed Journal: Trends Neurosci ISSN： 0166-2236 Impact factor: 13.837