BACKGROUND:Antioxidants applied topically and/or taken systemically may play an important role in counteracting the oxidative injury to lipids and proteins on the skin and eye that are provoked by radical oxygen species. OBJECTIVE: The aim of the study was to control photoprotective activity of the skin and eye through the use of oral antioxidants in 50 smoker volunteers (10 cigarettes/d) aged between 25-36 years and affected by dry skin. METHODS:Oxidative stress was assessed by a randomized double-blind study, and the ROS-Meter System (Dermotech, Rome, Italy). Global visual function was determined by the use of different visual surveillance tests. RESULTS: A 40% decrease of oxidative stress in blood serum was verified, with a clear relationship between global visual function and the oral intake of an oxygenated carotenoid (lutein). CONCLUSIONS: Carotenoids used as nutritional supplements seem to play an interesting photoprotective role for both skin and eyes, eventually increasing the activity of topical sunscreens.
RCT Entities:
BACKGROUND: Antioxidants applied topically and/or taken systemically may play an important role in counteracting the oxidative injury to lipids and proteins on the skin and eye that are provoked by radical oxygen species. OBJECTIVE: The aim of the study was to control photoprotective activity of the skin and eye through the use of oral antioxidants in 50 smoker volunteers (10 cigarettes/d) aged between 25-36 years and affected by dry skin. METHODS: Oxidative stress was assessed by a randomized double-blind study, and the ROS-Meter System (Dermotech, Rome, Italy). Global visual function was determined by the use of different visual surveillance tests. RESULTS: A 40% decrease of oxidative stress in blood serum was verified, with a clear relationship between global visual function and the oral intake of an oxygenated carotenoid (lutein). CONCLUSIONS:Carotenoids used as nutritional supplements seem to play an interesting photoprotective role for both skin and eyes, eventually increasing the activity of topical sunscreens.
Authors: Minu S Thomas; Michael Puglisi; Olga Malysheva; Marie A Caudill; Maria Sholola; Jessica L Cooperstone; Maria Luz Fernandez Journal: Nutrients Date: 2022-05-20 Impact factor: 6.706
Authors: Paul S Bernstein; François C Delori; Stuart Richer; Frederik J M van Kuijk; Adam J Wenzel Journal: Vision Res Date: 2009-10-23 Impact factor: 1.886
Authors: Lisa M Wilson; Saraniya Tharmarajah; Yuanxi Jia; Richard D Semba; Debra A Schaumberg; Karen A Robinson Journal: Adv Nutr Date: 2021-12-01 Impact factor: 8.701