OBJECTIVE: To analyze the features of organ dysfunction in severe acute respiratory syndrome (SARS) and the factors inducing multiple organ dysfunction syndrome (MODS) in these patients. METHODS: The clinical data of 135 SARS patients and 13 patients with severe SARS complicated by MODS were studied retrospectively. RESULTS: SARS could result in organ dysfunction. Its incidence rate was high, the patients' condition was severe, and the mortality was higher. SARS could end in MODS and the mortality was 92.3x. The main dysfunctioning organs were the lung (76.9x), the immune system (92.3x), the cardiovascular system (30.8x), the blood system (61.5x), the liver (38.5x), and the kidney (53.8x). CONCLUSION: Dysfunction of organs are closely correlated with prognosis of SARS. The causes of MODS in SARS are probably injury to the immune system and systemic inflammatory response syndrome.
OBJECTIVE: To analyze the features of organ dysfunction in severe acute respiratory syndrome (SARS) and the factors inducing multiple organ dysfunction syndrome (MODS) in these patients. METHODS: The clinical data of 135 SARSpatients and 13 patients with severe SARS complicated by MODS were studied retrospectively. RESULTS:SARS could result in organ dysfunction. Its incidence rate was high, the patients' condition was severe, and the mortality was higher. SARS could end in MODS and the mortality was 92.3x. The main dysfunctioning organs were the lung (76.9x), the immune system (92.3x), the cardiovascular system (30.8x), the blood system (61.5x), the liver (38.5x), and the kidney (53.8x). CONCLUSION: Dysfunction of organs are closely correlated with prognosis of SARS. The causes of MODS in SARS are probably injury to the immune system and systemic inflammatory response syndrome.
Authors: Michał Kukla; Karolina Skonieczna-Żydecka; Katarzyna Kotfis; Dominika Maciejewska; Igor Łoniewski; Luis F Lara; Monika Pazgan-Simon; Ewa Stachowska; Mariusz Kaczmarczyk; Anastasios Koulaouzidis; Wojciech Marlicz Journal: J Clin Med Date: 2020-05-11 Impact factor: 4.241
Authors: Jasjit S Suri; Anudeep Puvvula; Mainak Biswas; Misha Majhail; Luca Saba; Gavino Faa; Inder M Singh; Ronald Oberleitner; Monika Turk; Paramjit S Chadha; Amer M Johri; J Miguel Sanches; Narendra N Khanna; Klaudija Viskovic; Sophie Mavrogeni; John R Laird; Gyan Pareek; Martin Miner; David W Sobel; Antonella Balestrieri; Petros P Sfikakis; George Tsoulfas; Athanasios Protogerou; Durga Prasanna Misra; Vikas Agarwal; George D Kitas; Puneet Ahluwalia; Raghu Kolluri; Jagjit Teji; Mustafa Al Maini; Ann Agbakoba; Surinder K Dhanjil; Meyypan Sockalingam; Ajit Saxena; Andrew Nicolaides; Aditya Sharma; Vijay Rathore; Janet N A Ajuluchukwu; Mostafa Fatemi; Azra Alizad; Vijay Viswanathan; Pudukode R Krishnan; Subbaram Naidu Journal: Comput Biol Med Date: 2020-08-14 Impact factor: 4.589