Literature DB >> 15534400

Thoracic spondylitis from a mycotic (Streptococcus pneumoniae) aortic aneurysm: a case report.

Carsten Englert1, Hermann Aebert, Markus Lenhart, Albert Solleder, Michael Nerlich, Carsten Neumann.   

Abstract

STUDY
DESIGN: We report on a 54-year-old man with chronic lower back pain after recent streptococcus pneumoniae pulmonary infection, resulting in a mycotic aortic aneurysm and spondylodiscitis of the eighth vertebrae 6 months later. Successful surgical treatment and recurrence-free survival after 4 years are described. SUMMARY OF BACKGROUND DATA: Osteomyelitis by Streptococcus pneumoniae of the spine combined with contained rupture of a mycotic aortic aneurysm into lung and spine has not been reported to date. Mycotic aneurysms with pulmonary fistulas are reported to carry a mortality rate of up to 100%. Few cases have been reported with different operative and conservative strategies.
METHODS: The mycotic aortic aneurysm was excised using extracorporeal circulation and replaced by a Dacron graft. The spondylitic section of the eighth thoracic vertebrae was radically resected, and a tricortical bone block from the iliac crest was inserted into the defect. To keep compartments separated, collagen sponges with antibiotic supplementation were used. A triple antibiotic therapy (Metronidazol 3 x 0.5 g/day, Cefotaxim 3 x 2 g/day, and Flucloxacillin 3 x 2 g/day) was prescribed for 6 weeks and changed to Clindamycin for 1 year thereafter.
RESULTS: The patient made a good recovery and is free of recurrence 4 years after surgery.
CONCLUSIONS: Lower back pain might be a projected pain. Particularly in older patients or in the presence of comorbidities resulting in an immunocompromised status, an aggressive workup may be indicated. Radical resection of inflammatory tissues, sparse use of implant material, and prolonged administration of antibiotics proved a successful strategy in this patient.

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Year:  2004        PMID: 15534400     DOI: 10.1097/01.brs.0000137061.79898.8f

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  5 in total

1.  Unusual femoral artery mycotic aneurysm complicated by infective spondylitis.

Authors:  Wei-Che Lin; Chun-Chung Lui; Chen-Hsiang Lee; Hung-Chen Wang
Journal:  Emerg Radiol       Date:  2007-07-10

Review 2.  Spinal and paraspinal pneumococcal infections-a review.

Authors:  D M Siddiq; D M Musher; R O Darouiche
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-01-31       Impact factor: 3.267

3.  Streptococcus pneumoniae mycotic aneurysm with contiguous vertebral discitis treated by endovascular aortic repair and antibiotics.

Authors:  Karen Watura; Michael Katsimihas; Martin Williams
Journal:  BMJ Case Rep       Date:  2013-06-24

4.  Pneumococcal vertebral osteomyelitis at three teaching hospitals in Japan, 2003-2011: analysis of 14 cases and a review of the literature.

Authors:  Hiromichi Suzuki; Daisuke Shichi; Yasuharu Tokuda; Hiroichi Ishikawa; Tetsuhiro Maeno; Hidenori Nakamura
Journal:  BMC Infect Dis       Date:  2013-11-08       Impact factor: 3.090

5.  Vertebral Osteomyelitis Secondary to Pneumococcal Infection.

Authors:  Bindu Gandrapu; Preeyanka Sundar; Paula Aucoin
Journal:  Case Rep Infect Dis       Date:  2018-10-08
  5 in total

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