| Literature DB >> 15534271 |
F Blaes1, K Schmitz, M Tschernatsch, M Kaps, I Krasenbrink, G Hempelmann, M E Bräu.
Abstract
Sera of 12 patients with complex regional pain syndrome (CRPS) were tested for the occurrence of autoantibodies against nervous system structures. Immunohistochemistry revealed autoantibodies against autonomic nervous system structures in 5 of 12 (41.6%) of the patients. Western blot analysis showed neuronal reactivity in 11 of 12 (91.6%) patients. The authors hypothesize that CRPS can result from an autoimmune process against the sympathetic nervous system.Entities:
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Year: 2004 PMID: 15534271 DOI: 10.1212/01.wnl.0000143066.58498.ba
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910