Literature DB >> 15533182

Effective HIV treatment and the employment of HIV(+) adults.

Dana P Goldman1, Yuhua Bao.   

Abstract

OBJECTIVE: To examine whether highly active antiretroviral therapy (HAART) helps HIV-infected patients return to work, remain employed, and maintain hours of work. DATA SOURCE: Longitudinal data from a national probability sample of HIV+ patients older than 18 years old who made at least one visit in the contiguous United States in early 1996. STUDY
DESIGN: We consider the effect of HAART on three employment outcomes: (1) returning to work within six months of treatment, conditional on not working pretreatment; (2) remaining employed within six months of treatment, conditional on working pretreatment; (3) hours of work conditional on working at the second follow-up survey. We use a bivariate probit model to jointly model employment and treatment with HAART for the first two outcomes and the two-stage least squares method for hours of work. State policies regarding prescription drug coverage are used as instrumental variables for HAART to account for a key source of potential bias-the more severely ill tend to have the most difficulty working, but are also the most likely to be on HAART. PRINCIPAL
FINDINGS: Our results indicate that HAART increases the probability of remaining employed by HIV patients and hours of work for those working within six months of treatment. In the case of remaining employed, the employment effect (an increase from 58 percent to 94 percent in the probability of remaining employed) is statistically significant and the related incremental income is sizable compared to the incremental costs of HAART. Sensitivity analyses demonstrate that the results are robust to different specifications for insurance coverage.
CONCLUSIONS: Patients who are working are more likely to remain employed because of treatment with HAART. HAART prescribed to patients in less advanced stages of the infection may lead to the greatest gain in employment.

Entities:  

Mesh:

Year:  2004        PMID: 15533182      PMCID: PMC1361093          DOI: 10.1111/j.1475-6773.2004.00313.x

Source DB:  PubMed          Journal:  Health Serv Res        ISSN: 0017-9124            Impact factor:   3.402


  12 in total

1.  Labor market costs of illness: prevalence matters.

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2.  The care of HIV-infected adults in the United States. HIV Cost and Services Utilization Study Consortium.

Authors:  S A Bozzette; S H Berry; N Duan; M R Frankel; A A Leibowitz; D Lefkowitz; C A Emmons; J W Senterfitt; M L Berk; S C Morton; M F Shapiro
Journal:  N Engl J Med       Date:  1998-12-24       Impact factor: 91.245

3.  The impact of state policy on the costs of HIV infection.

Authors:  D P Goldman; J Bhattacharya; A A Leibowitz; G F Joyce; M F Shapiro; S A Bozzette
Journal:  Med Care Res Rev       Date:  2001-03       Impact factor: 3.929

4.  Access of vulnerable groups to antiretroviral therapy among persons in care for HIV disease in the United States. HCSUS Consortium. HIV Cost and Services Utilization Study.

Authors:  R Andersen; S Bozzette; M Shapiro; P St Clair; S Morton; S Crystal; D Goldman; N Wenger; A Gifford; A Leibowitz; S Asch; S Berry; T Nakazono; K Heslin; W Cunningham
Journal:  Health Serv Res       Date:  2000-06       Impact factor: 3.402

5.  Variations in the care of HIV-infected adults in the United States: results from the HIV Cost and Services Utilization Study.

Authors:  M F Shapiro; S C Morton; D F McCaffrey; J W Senterfitt; J A Fleishman; J F Perlman; L A Athey; J W Keesey; D P Goldman; S H Berry; S A Bozzette
Journal:  JAMA       Date:  1999 Jun 23-30       Impact factor: 56.272

6.  The use of highly active antiretroviral therapy (HAART) in patients with advanced HIV infection: impact on medical, palliative care, and quality of life outcomes.

Authors:  J R Brechtl; W Breitbart; M Galietta; S Krivo; B Rosenfeld
Journal:  J Pain Symptom Manage       Date:  2001-01       Impact factor: 3.612

7.  Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.

Authors:  F J Palella; K M Delaney; A C Moorman; M O Loveless; J Fuhrer; G A Satten; D J Aschman; S D Holmberg
Journal:  N Engl J Med       Date:  1998-03-26       Impact factor: 91.245

8.  Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study. Swiss HIV Cohort Study.

Authors:  M Egger; B Hirschel; P Francioli; P Sudre; M Wirz; M Flepp; M Rickenbach; R Malinverni; P Vernazza; M Battegay
Journal:  BMJ       Date:  1997-11-08

9.  Use of highly active antiretroviral therapy in a cohort of HIV-seropositive women.

Authors:  Judith A Cook; Mardge H Cohen; Dennis Grey; Lynn Kirstein; Jane Burke; Kathryn Anastos; Herminia Palacio; Jean Richardson; Tracey E Wilson; Mary Young
Journal:  Am J Public Health       Date:  2002-01       Impact factor: 9.308

10.  The exclusion of the elderly and women from clinical trials in acute myocardial infarction.

Authors:  J H Gurwitz; N F Col; J Avorn
Journal:  JAMA       Date:  1992-09-16       Impact factor: 56.272

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  21 in total

1.  Burden of HIV disease and comorbidities on the chances of maintaining employment in the era of sustained combined antiretoviral therapies use.

Authors:  Rosemary Dray-Spira; Camille Legeai; Mariette Le Den; François Boué; Caroline Lascoux-Combe; Anne Simon; Thierry May; Cécile Goujard; Laurence Meyer
Journal:  AIDS       Date:  2012-01-14       Impact factor: 4.177

2.  Highly active antiretroviral therapy and employment status in accra, ghana.

Authors:  Iw Howley; M Lartey; J T Machan; E A Talbot; A Obo-Akwa; T P Flanigan; A Kwara
Journal:  Ghana Med J       Date:  2010-12

3.  Employment predicts decreased mortality among HIV-seropositive illicit drug users in a setting of universal HIV care.

Authors:  Lindsey A Richardson; M-J S Milloy; Thomas H Kerr; Surita Parashar; Julio S G Montaner; Evan Wood
Journal:  J Epidemiol Community Health       Date:  2013-10-23       Impact factor: 3.710

Review 4.  Use of instrumental variable in prescription drug research with observational data: a systematic review.

Authors:  Yong Chen; Becky A Briesacher
Journal:  J Clin Epidemiol       Date:  2010-12-16       Impact factor: 6.437

5.  Socioeconomic differences in the impact of HIV infection on workforce participation in France in the era of highly active antiretroviral therapy.

Authors:  Rosemary Dray-Spira; Alice Gueguen; Jean-François Ravaud; France Lert
Journal:  Am J Public Health       Date:  2007-01-31       Impact factor: 9.308

6.  Disease severity, self-reported experience of workplace discrimination and employment loss during the course of chronic HIV disease: differences according to gender and education.

Authors:  R Dray-Spira; A Gueguen; F Lert
Journal:  Occup Environ Med       Date:  2007-11-02       Impact factor: 4.402

7.  Work-related barriers and facilitators to antiretroviral therapy adherence in persons living with HIV infection.

Authors:  Gilberto Torres-Madriz; Debra Lerner; Robin Ruthazer; William H Rogers; Ira B Wilson
Journal:  AIDS Behav       Date:  2011-10

Review 8.  HIV and depression: 2008 review and update.

Authors:  Judith G Rabkin
Journal:  Curr HIV/AIDS Rep       Date:  2008-11       Impact factor: 5.071

9.  Determinants of health care costs of HIV-positive patients in the Canary Islands, Spain.

Authors:  Juan Oliva-Moreno; Julio López-Bastida; Pedro Serrano-Aguilar; Lilisbeth Perestelo-Pérez
Journal:  Eur J Health Econ       Date:  2010-01-05

10.  The economic costs and health-related quality of life of people with HIV/AIDS in the Canary Islands, Spain.

Authors:  Julio Lopez-Bastida; Juan Oliva-Moreno; Lilisbeth Perestelo-Perez; Pedro Serrano-Aguilar
Journal:  BMC Health Serv Res       Date:  2009-03-30       Impact factor: 2.655

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