BACKGROUND/AIMS: Acute renal failure after liver transplantation can occur in some and is an important postoperative complication. Our goal is to clarify the risk factors of acute renal failure after living-related donor liver transplantation (LDLT). METHODOLOGY: From March 1999 to August 2000, ten consecutive patients were investigated the changes of the systemic hemodynamics and the renal function. They were classified into Group A (Creatinine (Cre) was over 2.0 mg/dL) and B (Cre was below 2.0 mg/dL). Retrospective variables were examined with two groups A and B being compared. RESULTS: In both groups, Cardiac Index (CI) was above standard levels. However, the CI levels in Group B were significantly higher than those in Group A (p=0.031). The early postoperative transaminase levels were significantly higher in Group A than in Group B (p=0.049) and graft liver volume/recipient body weight ratio was significantly smaller in Group A than in Group B (p=0.016). CONCLUSIONS: Our study suggests that small-for-size graft or hypovolemia, resulting in the delay of the recovery of graft liver function, may be an important cause of acute renal failure during the early postoperative period in adult LDLT.
BACKGROUND/AIMS: Acute renal failure after liver transplantation can occur in some and is an important postoperative complication. Our goal is to clarify the risk factors of acute renal failure after living-related donor liver transplantation (LDLT). METHODOLOGY: From March 1999 to August 2000, ten consecutive patients were investigated the changes of the systemic hemodynamics and the renal function. They were classified into Group A (Creatinine (Cre) was over 2.0 mg/dL) and B (Cre was below 2.0 mg/dL). Retrospective variables were examined with two groups A and B being compared. RESULTS: In both groups, Cardiac Index (CI) was above standard levels. However, the CI levels in Group B were significantly higher than those in Group A (p=0.031). The early postoperative transaminase levels were significantly higher in Group A than in Group B (p=0.049) and graft liver volume/recipient body weight ratio was significantly smaller in Group A than in Group B (p=0.016). CONCLUSIONS: Our study suggests that small-for-size graft or hypovolemia, resulting in the delay of the recovery of graft liver function, may be an important cause of acute renal failure during the early postoperative period in adult LDLT.
Authors: Ibtesam A Hilmi; Daniela Damian; Ali Al-Khafaji; Tetsuro Sakai; Joseph Donaldson; Daniel G Winger; John A Kellum Journal: Liver Transpl Date: 2015-07-21 Impact factor: 5.799
Authors: Min Suk Chae; Hyunjoon Park; Ho Joong Choi; Misun Park; Hyun Sik Chung; Sang Hyun Hong; Chul Soo Park; Jong Ho Choi; Hyung Mook Lee Journal: PLoS One Date: 2018-12-17 Impact factor: 3.240
Authors: Min Suk Chae; Nuri Lee; Da Hye Park; Jisoo Lee; Hyun Sik Jung; Chul Soo Park; Jaemin Lee; Jong Ho Choi; Sang Hyun Hong Journal: Medicine (Baltimore) Date: 2017-08 Impact factor: 1.889