Literature DB >> 15531102

Time dependent alterations in dopamine tissue levels and metabolism after experimental traumatic brain injury in rats.

Jaime L Massucci1, Anthony E Kline, Xiecheng Ma, Ross D Zafonte, C Edward Dixon.   

Abstract

Several studies have demonstrated alterations in the dopamine (DA) system after traumatic brain injury (TBI). The present study investigated the temporal changes in DA tissue levels and metabolism at 1-h or 1, 7, 14, and 28 days after cortical impact or sham injury in rats. DA and DOPAC levels were measured by HPLC in the frontal cortex (FC) and striatum. DA levels were significantly increased at 1h in the contralateral FC and at 1 day in the ipsilateral FC versus respective sham groups. DA and DOPAC levels were significantly increased bilaterally at 1h in the striatum versus sham. These data indicate that TBI induces an early increase in DA and DOPAC, which returns to sham levels over time.

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Year:  2004        PMID： 15531102     DOI： 10.1016/j.neulet.2004.09.026

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  32 in total

1.  Targeting Dopamine in Acute Traumatic Brain Injury.

Authors:  James W Bales; Anthony E Kline; Amy K Wagner; C Edward Dixon
Journal:  Open Drug Discov J       Date:  2010

Review 2.  Catecholaminergic based therapies for functional recovery after TBI.

Authors:  Nicole D Osier; C Edward Dixon
Journal:  Brain Res       Date:  2015-12-19       Impact factor: 3.252

3.  Differential effects of single versus multiple administrations of haloperidol and risperidone on functional outcome after experimental brain trauma.

Authors:  Anthony E Kline; Jaime L Massucci; Roos D Zafonte; C Edward Dixon; Judith R DeFeo; Emily H Rogers
Journal:  Crit Care Med       Date:  2007-03       Impact factor: 7.598

Review 4.  Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies.

Authors:  Jennifer L McGuire; Laura B Ngwenya; Robert E McCullumsmith
Journal:  Mol Psychiatry       Date:  2018-09-13       Impact factor: 15.992

5.  Traumatic brain injury reduces striatal tyrosine hydroxylase activity and potassium-evoked dopamine release in rats.

Authors:  Samuel S Shin; Eric R Bray; Cathy Q Zhang; C Edward Dixon
Journal:  Brain Res       Date:  2010-11-01       Impact factor: 3.252

6.  Spontaneous recovery after controlled cortical impact injury is not impeded by intermittent administration of the antipsychotic drug risperidone.

Authors:  Lauren J Carlson; Gina C Bao; Sonya Besagar; Jacob B Leary; Hannah L Radabaugh; Corina O Bondi; Anthony E Kline
Journal:  Neurosci Lett       Date:  2018-06-06       Impact factor: 3.046

7.  Chronic administration of antipsychotics impede behavioral recovery after experimental traumatic brain injury.

Authors:  Anthony E Kline; Ann N Hoffman; Jeffrey P Cheng; Ross D Zafonte; Jaime L Massucci
Journal:  Neurosci Lett       Date:  2008-10-25       Impact factor: 3.046

8.  Fast-scan cyclic voltammetry demonstrates that L-DOPA produces dose-dependent, regionally selective bimodal effects on striatal dopamine kinetics in vivo.

Authors:  Rashed Harun; Kristin M Hare; Elizabeth M Brough; Miranda J Munoz; Christine M Grassi; Gonzalo E Torres; Anthony A Grace; Amy K Wagner
Journal:  J Neurochem       Date:  2016-01-13       Impact factor: 5.372

Review 9.  5-hydroxytryptamine1A (5-HT1A) receptor agonists: A decade of empirical evidence supports their use as an efficacious therapeutic strategy for brain trauma.

Authors:  Jeffrey P Cheng; Jacob B Leary; Aerin Sembhi; Clarice M Edwards; Corina O Bondi; Anthony E Kline
Journal:  Brain Res       Date:  2015-11-21       Impact factor: 3.252

10.  Juvenile Traumatic Brain Injury Increases Alcohol Consumption and Reward in Female Mice.

Authors:  Zachary M Weil; Kate Karelina; Kristopher R Gaier; Timothy E D Corrigan; John D Corrigan
Journal:  J Neurotrauma       Date:  2015-10-08       Impact factor: 5.269
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