Literature DB >> 1552817

Segregation of the growth slowing effects of valproic acid from phenytoin and carbamazepine on lymphoid tumor cells.

T V Tittle1, B A Schaumann, J E Rainey, K Taylor.   

Abstract

One human and six murine tumor cell lines of lymphoid origin were assessed for growth in the presence of three commonly used antiepileptic drugs (AEDs). All seven lines were sensitive to the growth slowing effects of phenytoin (PHT) and carbamazepine (CBZ). Six lines showed a similar effect when exposed to valproic acid (VPA), while one murine B cell line was resistant to inhibition of growth by VPA.

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Year:  1992        PMID: 1552817     DOI: 10.1016/0024-3205(92)90104-w

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  2 in total

1.  Sodium valproate facilitates the propagation of granulocytic ehrlichiae (Anaplasma phagocytophilum) in HL-60 cells.

Authors:  Petir Zeman; Jaroslav Cinatl; Hana Kabickova
Journal:  Exp Appl Acarol       Date:  2002       Impact factor: 2.132

Review 2.  Voltage-gated sodium channel as a target for metastatic risk reduction with re-purposed drugs.

Authors:  Tomas Koltai
Journal:  F1000Res       Date:  2015-07-22
  2 in total

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