| Literature DB >> 15528076 |
Abstract
T-cell immunological memory consists largely of clones of proliferating lymphocytes maintained by antigenic stimulation and the survival and proliferative effects of cytokines. The duration of survival of memory clones in humans is determine by the Hayflick limit on the number of cell divisions, the rate of cycling of memory cells and factors that control erosion of telomeres, including mechanisms that control telomerase.Entities:
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Year: 2004 PMID: 15528076 DOI: 10.1016/j.smim.2004.08.012
Source DB: PubMed Journal: Semin Immunol ISSN: 1044-5323 Impact factor: 11.130