| Literature DB >> 15527300 |
Neelakandha S Mani1, Jill A Jablonowski, Todd K Jones.
Abstract
Starting from 1-methylimidazole, a concise, scalable, three-step synthesis of the title compound is described. The required 2-chloroimidazole was prepared in very good yield by halogen-metal exchange between the 2-lithio derivative and hexachloroethane.Entities:
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Year: 2004 PMID: 15527300 DOI: 10.1021/jo040225i
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354