Literature DB >> 15526152

Cys-tRNACys formation and cysteine biosynthesis in methanogenic archaea: two faces of the same problem?

A Ambrogelly1, S Kamtekar, A Sauerwald, B Ruan, D Tumbula-Hansen, D Kennedy, I Ahel, D Söll.   

Abstract

Aminoacyl-tRNA (transfer RNA) synthetases are essential components of the cellular translation machinery as they provide the ribosome with aminoacyl-tRNAs. Aminoacyl-tRNA synthesis is generally well understood. However, the mechanism of Cys-tRNACys formation in three methanogenic archaea ( Methanocaldococcus jannaschii, Methanothermobacter thermautotrophicus and Methanopyrus kandleri) is still unknown, since no recognizable gene for a canonical cysteinyl-tRNA synthetase could be identified in the genome sequences of these organisms. Here we review the different routes recently proposed for Cys-tRNACys formation and discuss its possible link with cysteine biosynthesis in these methanogenic archaea.

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Year:  2004        PMID： 15526152     DOI： 10.1007/s00018-004-4194-9

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN： 1420-682X            Impact factor:   9.261


  38 in total

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4.  Noninvasive panoramic mapping of human atrial fibrillation mechanisms: a feasibility report.

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5.  Phrenic nerve paralysis during cryoballoon ablation for atrial fibrillation: a comparison between the first- and second-generation balloon.

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6.  Improved procedural efficacy of pulmonary vein isolation using the novel second-generation cryoballoon.

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7.  Cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation: first results of the North American Arctic Front (STOP AF) pivotal trial.

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10.  Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial.

Authors:  Demosthenes G Katritsis; Evgeny Pokushalov; Alexander Romanov; Eleftherios Giazitzoglou; George C M Siontis; Sunny S Po; A John Camm; John P A Ioannidis
Journal:  J Am Coll Cardiol       Date:  2013-08-21       Impact factor: 24.094
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  2 in total

1.  Catalytic mechanism of Sep-tRNA:Cys-tRNA synthase: sulfur transfer is mediated by disulfide and persulfide.

Authors:  Yuchen Liu; Patricia C Dos Santos; Xiang Zhu; Ron Orlando; Dennis R Dean; Dieter Söll; Jing Yuan
Journal:  J Biol Chem       Date:  2011-12-13       Impact factor: 5.157

2.  Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei.

Authors:  Scott I Hauenstein; John J Perona
Journal:  J Biol Chem       Date:  2008-06-17       Impact factor: 5.157
  2 in total

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