| Literature DB >> 15526143 |
S Anttila1, A Illi, O Kampman, K M Mattila, T Lehtimäki, E Leinonen.
Abstract
Several studies have connected brain-derived neurotrophic factor (BDNF) with treatment response to neuroleptics. In recent studies, the BDNF expression was reduced by typical neuroleptics. We conducted a retrospective study on 94 patients with schizophrenia and 98 controls. The BDNF G196A and C270T polymorphisms are not associated with treatment response to typical neuroleptics or with age at first hospitalization. Moreover, these polymorphisms of the BDNF gene are not associated with the risk of schizophrenia.Entities:
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Year: 2004 PMID: 15526143 DOI: 10.1007/s00702-004-0233-9
Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN: 0300-9564 Impact factor: 3.575