Literature DB >> 15526143

Lack of association between two polymorphisms of brain-derived neurotrophic factor and response to typical neuroleptics.

S Anttila1, A Illi, O Kampman, K M Mattila, T Lehtimäki, E Leinonen.   

Abstract

Several studies have connected brain-derived neurotrophic factor (BDNF) with treatment response to neuroleptics. In recent studies, the BDNF expression was reduced by typical neuroleptics. We conducted a retrospective study on 94 patients with schizophrenia and 98 controls. The BDNF G196A and C270T polymorphisms are not associated with treatment response to typical neuroleptics or with age at first hospitalization. Moreover, these polymorphisms of the BDNF gene are not associated with the risk of schizophrenia.

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Year:  2004        PMID: 15526143     DOI: 10.1007/s00702-004-0233-9

Source DB:  PubMed          Journal:  J Neural Transm (Vienna)        ISSN: 0300-9564            Impact factor:   3.575


  14 in total

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5.  Pharmacogenetics of Antipsychotic Treatment in Schizophrenia.

Authors:  Samar S M Elsheikh; Daniel J Müller; Jennie G Pouget
Journal:  Methods Mol Biol       Date:  2022

6.  Genetic variants in the BDNF gene and therapeutic response to risperidone in schizophrenia patients: a pharmacogenetic study.

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7.  Association of the brain-derived neurotrophic factor gene G196A rs6265 polymorphisms and the cognitive function and clinical symptoms of schizophrenia.

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8.  Association between the brain-derived neurotrophic factor Val66Met polymorphism and therapeutic response to olanzapine in schizophrenia patients.

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9.  BDNF and schizophrenia: from neurodevelopment to neuronal plasticity, learning, and memory.

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Review 10.  Brain-derived neurotrophic factor and schizophrenia.

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Journal:  Psychiatr Genet       Date:  2019-10       Impact factor: 2.574

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