Literature DB >> 15523855

Uterine fibroid: a review.

B O Akinyemi1, B R Adewoye, T A Fakoya.   

Abstract

BACKGROUND: Uterine fibroid is a benign tumour of uterine smooth muscle. The purpose of this review is to bring to light the current spectra of presentation and management status of this benign and very important cause of menstrual and fertility disturbance in African women and the Black race in general. This is especially so with the trivialization of its aetological factors and treatment by claims from alternative medical practitioners. This review, therefore sought to document what is currently known about the condition and what could possibly be done to achieve better results in its management.
METHODS: Literature on the subject above was reviewed using manual library search, electronic books such as CD-ROMS and journals articles published by various local and international authors on the subject; it also included internet search on relevant aspects of the topic.
RESULTS: Fibroid is the commonest benign tumour of the female genital tract, it contributes about 70 to 80% of new growths in the female genital tracts, it is a cause of significant morbidity in women of reproductive age group and when complicated could be a significant cause of mortality. Spectrum of presentation mainly involves disturbance of menstruation, reduction in fertility, pressure and obstructive symptoms and rarely malignant presentations. When recognized early effective conservative and definitive therapies are available to offer relief for women and to make their menstrual and reproductive life more meaningful.
CONCLUSION: From the literature reviewed, it was obvious that the subject of uterine fibroid is still not fully exhausted and there were a lot of research questions waiting to be answered on the aetiopathogenesis of the disease. There is also the need to fashion out better treatment alternatives that will reduce morbidity in the process of managing the patient as well as those that will further enhance reproductive potentials after treatment.

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Year:  2004        PMID: 15523855

Source DB:  PubMed          Journal:  Niger J Med        ISSN: 1115-2613


  8 in total

1.  [Non-invasive thermoablation of symptomatic uterine fibroids with magnetic resonance-guided high-energy ultrasound].

Authors:  T Eckey; A Neumann; M K Bohlmann; J Barkhausen; P Hunold
Journal:  Radiologe       Date:  2011-07       Impact factor: 0.635

2.  Identification of Polycomb Group Protein EZH2-Mediated DNA Mismatch Repair Gene MSH2 in Human Uterine Fibroids.

Authors:  Qiwei Yang; Archana Laknaur; Lelyand Elam; Nahed Ismail; Larisa Gavrilova-Jordan; John Lue; Michael P Diamond; Ayman Al-Hendy
Journal:  Reprod Sci       Date:  2016-03-31       Impact factor: 3.060

3.  Surgical management of uterine fibroids at aminu kano teaching hospital.

Authors:  Abiodun Omole-Ohonsi; Francis Belga
Journal:  Obstet Gynecol Int       Date:  2011-11-10

4.  Complete utero vaginal prolapse in a woman with prolapsed submucous fibroid.

Authors:  Uu Aniebue; To Nwankwo
Journal:  Ann Med Health Sci Res       Date:  2015 Jan-Feb

Review 5.  Transforming growth factor β signaling in uterine development and function.

Authors:  Qinglei Li
Journal:  J Anim Sci Biotechnol       Date:  2014-11-14

6.  Clinical Presentation of Uterine Fibroids in Nnewi, Nigeria: A 5-year Review.

Authors:  Co Ezeama; Ji Ikechebelu; Nj Obiechina; Nn Ezeama
Journal:  Ann Med Health Sci Res       Date:  2012-07

7.  The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids.

Authors:  Qiwei Yang; Sangeeta Nair; Archana Laknaur; Nahed Ismail; Michael P Diamond; Ayman Al-Hendy
Journal:  Biol Reprod       Date:  2016-02-17       Impact factor: 4.285

8.  Feasibility and Safety of Absorbable Knotless Wound Closure Device in Laparoscopic Myomectomy.

Authors:  Chying-Chyuan Chan; Ching-Yu Lee
Journal:  Biomed Res Int       Date:  2016-06-27       Impact factor: 3.411

  8 in total

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