Literature DB >> 15523495

Y chromosome evidence for a founder effect in Ashkenazi Jews.

Almut Nebel1, Dvora Filon, Marina Faerman, Himla Soodyall, Ariella Oppenheim.   

Abstract

Recent genetic studies, based on Y chromosome polymorphic markers, showed that Ashkenazi Jews are more closely related to other Jewish and Middle Eastern groups than to their host populations in Europe. However, Ashkenazim have an elevated frequency of R-M17, the dominant Y chromosome haplogroup in Eastern Europeans, suggesting possible gene flow. In the present study of 495 Y chromosomes of Ashkenazim, 57 (11.5%) were found to belong to R-M17. Detailed analyses of haplotype structure, diversity and geographic distribution suggest a founder effect for this haplogroup, introduced at an early stage into the evolving Ashkenazi community in Europe. R-M17 chromosomes in Ashkenazim may represent vestiges of the mysterious Khazars.

Mesh：

Year:  2005        PMID： 15523495     DOI： 10.1038/sj.ejhg.5201319

Source DB:  PubMed          Journal:  Eur J Hum Genet        ISSN： 1018-4813            Impact factor:   4.246


  9 in total

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Review 5.  The population genetics of the Jewish people.

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Authors:  Siiri Rootsi; Doron M Behar; Mari Järve; Alice A Lin; Natalie M Myres; Ben Passarelli; G David Poznik; Shay Tzur; Hovhannes Sahakyan; Ajai Kumar Pathak; Saharon Rosset; Mait Metspalu; Viola Grugni; Ornella Semino; Ene Metspalu; Carlos D Bustamante; Karl Skorecki; Richard Villems; Toomas Kivisild; Peter A Underhill
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  9 in total

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