| Literature DB >> 15523480 |
Nikolaus Pfanner1, Nils Wiedemann, Chris Meisinger, Trevor Lithgow.
Abstract
The general preprotein translocase of the outer mitochondrial membrane (TOM complex) transports virtually all mitochondrial precursor proteins, but cannot assemble outer-membrane precursors into functional complexes. A recently discovered sorting and assembly machinery (SAM complex) is essential for integration and assembly of outer-membrane proteins, revealing unexpected connections to mitochondrial evolution and morphology.Mesh:
Substances:
Year: 2004 PMID: 15523480 DOI: 10.1038/nsmb852
Source DB: PubMed Journal: Nat Struct Mol Biol ISSN: 1545-9985 Impact factor: 15.369