| Literature DB >> 1551973 |
A L Barry1, L B Reller, G H Miller, J A Washington, F D Schoenknect, L R Peterson, R S Hare, C Knapp.
Abstract
A multilaboratory study was undertaken to reassess the amount of calcium and magnesium that should be added to Mueller-Hinton broth when testing Pseudomonas aeruginosa against amikacin, gentamicin, isepamicin, netilmicin, and tobramycin. To achieve parity with agar dilution tests, cation-adjusted broth should contain 20 to 25 mg of calcium and 10 to 12.5 mg of magnesium per liter rather than the 50- and 25-mg/liter supplements recommended previously. For quality control of tests with contemporary media, MIC control limits should be adjusted by lowering the current MIC limits by at least 1 doubling-dilution interval.Entities:
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Year: 1992 PMID: 1551973 PMCID: PMC265114 DOI: 10.1128/jcm.30.3.585-589.1992
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948