Literature DB >> 15519095

Comparison of the biomechanical behavior of foldable intraocular lenses.

Stephen S Lane1, Paula Burgi, Gregory S Milios, Michael W Orchowski, Michael Vaughan, Eric Schwarte.   

Abstract

PURPOSE: To compare a standardized battery of biomechanical laboratory tests to assess the performance of popular foldable intraocular lenses (IOLs).
SETTING: Biomedical testing facilities, Alcon Research, Ltd., Fort Worth, Texas, USA.
METHODS: Using industry-standard biomechanical testing techniques, 1- and 3-piece foldable IOLs (Alcon AcrySof MA60BM, MA30BA, SA30AL, SA60AT; Allergan Sensar AR40, PhacoFlex II SI-40NB; Bausch & Lomb Soflex LI61U; Pharmacia & Upjohn CeeOn 920) and a 1-piece all-poly(methyl methacrylate) (PMMA) IOL (Alcon MZ30BD) were tested under identical conditions with regard to (1) tensile/elastic properties by comparing haptic pull strength and haptic elongation and (2) compression properties by comparing haptic compression forces, haptic compression force decay over time, and axial displacement. All tests were performed with the IOLs submersed in a controlled-temperature water bath (mean 35 degrees C +/- 2 degrees C [SD]).
RESULTS: For all IOLs, the ultimate elongation and pull strength of the haptics before failure was highest with the Alcon SA30AL and SA60AT. Similarly, the force required to compress haptics to a prescribed 10.0 mm diameter was least with the SA30AL and the SA60AT lenses. These 1-piece lenses also showed the least decay of residual compression force as a function of time. Optic displacement along the optical axis with haptic compression to 10.0 mm was least with the Alcon 1-piece IOLs and the all-PMMA control IOL.
CONCLUSION: AcrySof 1-piece SA30AL and SA60AT IOLs demonstrated superior biomechanical characteristics over other foldable IOL designs.

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Year:  2004        PMID: 15519095     DOI: 10.1016/j.jcrs.2004.03.041

Source DB:  PubMed          Journal:  J Cataract Refract Surg        ISSN: 0886-3350            Impact factor:   3.351


  14 in total

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6.  Short-term Dynamics after Single- and Three-piece Acrylic Intraocular Lens Implantation: A Swept-source Anterior Segment Optical Coherence Tomography Study.

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8.  The efficacy of an acrylic intraocular lens surface modified with polyethylene glycol in posterior capsular opacification.

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Journal:  J Korean Med Sci       Date:  2007-06       Impact factor: 2.153

9.  Cyclodextrin-containing hydrogels as an intraocular lens for sustained drug release.

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10.  Long-term effectiveness and safety of a three-piece acrylic hydrophobic intraocular lens modified with hydroxyethyl-methacrylate: an open-label, 3-year follow-up study.

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Journal:  Clin Ophthalmol       Date:  2018-10-11
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