| Literature DB >> 15517373 |
Evariste Gafumbegete1, Susann Richter, Ludwig Jonas, Horst Nizze, Josef Makovitzky.
Abstract
We report a case concerning a 49-year-old female patient with thoracic pain. X-rays showed a single osteolytic lesion on the right seventh rib. The excision of the rib disclosed a plasmocytic plasmocytoma with extensive amyloidosis. Serum and urine protein electrophoresis were both negative for monoclonal gammopathy. Bone marrow biopsy showed that 80% of the marrow had been replaced by plasma cells. A diagnosis of nonsecretory multiple myeloma was made. Immunohistochemistry revealed amyloid light (AL) amyloidosis of kappa-light chain origin. The relationship between nonsecretory multiple myeloma and amyloidosis is discussed.Entities:
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Year: 2004 PMID: 15517373 DOI: 10.1007/s00428-004-1084-3
Source DB: PubMed Journal: Virchows Arch ISSN: 0945-6317 Impact factor: 4.064