Literature DB >> 15517303

[Panzytopenia from combination therapy with azathioprin and allopurinol].

W Seidel1.   

Abstract

Azathioprine has been used in rheumatology for more than twenty years. Indications are collagen diseases with multiorgan involvement, where co-medications are frequently necessary. We describe a patient suffering from pancytopenia following a combination therapy of azathioprine and allopurinol because of lupus erythematodes and diabetic nephropathy with hyperuricemia.

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Year:  2004        PMID： 15517303     DOI： 10.1007/s00393-004-0551-1

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN： 0340-1855            Impact factor:   1.372


  12 in total

1.  The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations.

Authors:  E S Collie-Duguid; S C Pritchard; R H Powrie; J Sludden; D A Collier; T Li; H L McLeod
Journal:  Pharmacogenetics       Date:  1999-02

2.  Azathioprine metabolism: pharmacokinetics of 6-mercaptopurine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients.

Authors:  G L Chan; G R Erdmann; S A Gruber; A J Matas; D M Canafax
Journal:  J Clin Pharmacol       Date:  1990-04       Impact factor: 3.126

3.  Azathioprine and allopurinol: the price of an avoidable drug interaction.

Authors:  D T Kennedy; M S Hayney; K D Lake
Journal:  Ann Pharmacother       Date:  1996-09       Impact factor: 3.154

4.  [Pancytopenia following a combination therapy with allopurinol and azathioprine. Discussion contribution and conclusion].

Authors:  G Stockhausen; U Hopf; P Glogner
Journal:  Med Welt       Date:  1977-01-28

5.  [Medullar aplasia due to concomitant use of azathioprine and allopurinol in kidney transplantation. Probable beneficial effects of infusion of leukemic cells].

Authors:  A J Mocelin; E T Hager; C B Carpenter; J P Merrill
Journal:  AMB Rev Assoc Med Bras       Date:  1976-05

6.  Interaction of allopurinol with 6-mercaptopurine and azathioprine.

Authors:  R J Brooks; R T Dorr; B G Durie
Journal:  Biomed Pharmacother       Date:  1982       Impact factor: 6.529

7.  Increased danger of bone marrow damage in simultaneous azathioprine-allopurinol therapy.

Authors:  J Zazgornik; H Kopsa; P Schmidt; P Pils; K Kuschan; E Deutsch
Journal:  Int J Clin Pharmacol Ther Toxicol       Date:  1981-03

8.  Pharmacokinetics, dose adjustments, and 6-mercaptopurine/methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency.

Authors:  J B Andersen; C Szumlanski; R M Weinshilboum; K Schmiegelow
Journal:  Acta Paediatr       Date:  1998-01       Impact factor: 2.299

Review 9.  Azathioprine: state of the art in inflammatory bowel disease.

Authors:  W J Sandborn
Journal:  Scand J Gastroenterol Suppl       Date:  1998

Review 10.  Methylation pharmacogenetics: thiopurine methyltransferase as a model system.

Authors:  R M Weinshilboum
Journal:  Xenobiotica       Date:  1992 Sep-Oct       Impact factor: 1.908
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