H C Steinert1. 1. Klinik und Poliklinik für Nuklearmedizin, Universitätsspital Zürich, Schweiz. hans.steinert@usz.ch
Abstract
PURPOSE: First results of PET/CT in Hodgkin's disease (HD) and aggressive non-Hodgkin's lymphoma (NHL) are reported. PATIENTS AND METHODS: From March 2001 to August 2004 822 PET/CT were performed at our clinic in lymphoma patients for primary staging, restaging after therapy, and diagnosis of recurrence. For coregistration non contrast-enhanced low-dose CT were used. RESULTS: Due to the exact anatomic localization of (18)F-FDG accumulating lesions equivocal or false positive PET findings are avoided. In comparison to contrast enhanced CT, PET/CT has a higher sensitivity and specificity in patients with HD and aggressive NHL. Integration of PET/CT in treatment planning of radiation therapy optimizes the field volume. CONCLUSION: Even in the initial phase of clinical evaluation, PET/CT has proven useful in staging and restaging of lymphoma. The exact anatomic localization of the PET findings is essential for a precise report, for treatment planning of radiation therapy, and for planning surgical biopsy.
PURPOSE: First results of PET/CT in Hodgkin's disease (HD) and aggressive non-Hodgkin's lymphoma (NHL) are reported. PATIENTS AND METHODS: From March 2001 to August 2004 822 PET/CT were performed at our clinic in lymphomapatients for primary staging, restaging after therapy, and diagnosis of recurrence. For coregistration non contrast-enhanced low-dose CT were used. RESULTS: Due to the exact anatomic localization of (18)F-FDG accumulating lesions equivocal or false positive PET findings are avoided. In comparison to contrast enhanced CT, PET/CT has a higher sensitivity and specificity in patients with HD and aggressive NHL. Integration of PET/CT in treatment planning of radiation therapy optimizes the field volume. CONCLUSION: Even in the initial phase of clinical evaluation, PET/CT has proven useful in staging and restaging of lymphoma. The exact anatomic localization of the PET findings is essential for a precise report, for treatment planning of radiation therapy, and for planning surgical biopsy.
Authors: Niklaus G Schaefer; Thomas F Hany; Christian Taverna; Burkhardt Seifert; Katrin D M Stumpe; Gustav K von Schulthess; Gerhard W Goerres Journal: Radiology Date: 2004-07-23 Impact factor: 11.105
Authors: Elena V Dizendorf; Brigitta G Baumert; Gustav K von Schulthess; Urs M Lütolf; Hans C Steinert Journal: J Nucl Med Date: 2003-01 Impact factor: 10.057
Authors: Thomas F Hany; Esmaiel Gharehpapagh; Ehab M Kamel; Alfred Buck; Jean Himms-Hagen; Gustav K von Schulthess Journal: Eur J Nucl Med Mol Imaging Date: 2002-08-08 Impact factor: 9.236
Authors: Christian la Fougère; Walter Hundt; Nicole Bröckel; Thomas Pfluger; Alexander Haug; Bernhard Scher; Marcus Hacker; Klaus Hahn; Maximilan Reiser; Reinhold Tiling Journal: Eur J Nucl Med Mol Imaging Date: 2006-07-21 Impact factor: 9.236