Literature DB >> 15516862

Beta blockers as anti-arrhythmic agents.

Daejoon Anh1, Joseph E Marine.   

Abstract

Although beta-adrenergic blocking agents are not always considered anti-arrhythmic drugs, the results of several recent trials have suggested an anti-arrhythmic mechanism for at least part of their mortality benefit in the treatment of chronic congestive heart failure. We review background experimental and clinical evidence for the anti-arrhythmic actions of beta-blockers and then review the results of published beta-blocker heart failure trials. A majority of trials showed improvement in overall survival as well as reduction in sudden death and ventricular arrhythmias with beta-blocker treatment. Although different effects were seen with different specific agents, these trials overall support a clinically significant anti-arrhythmic effect of several beta-blockers.

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Year:  2004        PMID： 15516862     DOI： 10.1023/B:HREV.0000046369.90417.db

Source DB:  PubMed          Journal:  Heart Fail Rev        ISSN： 1382-4147            Impact factor:   4.214


  65 in total

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2.  COMET: a proposed mechanism of action to explain the results and concerns about dose.

Authors:  Ake Hjalmarson; Finn Waagstein
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Review 3.  Influence of myocardial ischemia and infarction on autonomic innervation of heart.

Authors:  D P Zipes
Journal:  Circulation       Date:  1990-10       Impact factor: 29.690

Review 4.  Sudden death in coronary artery disease: acute ischemia versus myocardial substrate.

Authors:  D Mehta; J Curwin; J A Gomes; V Fuster
Journal:  Circulation       Date:  1997-11-04       Impact factor: 29.690

Review 5.  Beta-adrenergic blocker mortality trials in congestive heart failure.

Authors:  J R Teerlink; B M Massie
Journal:  Am J Cardiol       Date:  1999-11-04       Impact factor: 2.778

6.  Sudden death in patients with implantable cardioverter defibrillators: the importance of post-shock electromechanical dissociation.

Authors:  L Brent Mitchell; Edgar A Pineda; Jack L Titus; Paulette M Bartosch; David G Benditt
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Review 7.  Sympathetic nerve sprouting, electrical remodeling and the mechanisms of sudden cardiac death.

Authors:  P S Chen; L S Chen; J M Cao; B Sharifi; H S Karagueuzian; M C Fishbein
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Authors:  F Hartmann; S Ziegler; S Nekolla; M Hadamitzky; M Seyfarth; G Richardt; M Schwaiger
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9.  A randomized trial of beta-blockade in heart failure. The Cardiac Insufficiency Bisoprolol Study (CIBIS). CIBIS Investigators and Committees.

Authors: 
Journal:  Circulation       Date:  1994-10       Impact factor: 29.690

Review 10.  Sudden cardiac death in heart failure. The role of abnormal repolarization.

Authors:  G F Tomaselli; D J Beuckelmann; H G Calkins; R D Berger; P D Kessler; J H Lawrence; D Kass; A M Feldman; E Marban
Journal:  Circulation       Date:  1994-11       Impact factor: 29.690
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