Literature DB >> 15514592

Valve-sparing aortic root replacement in bicuspid aortic valves: a reasonable option?

Diana Aicher1, Frank Langer, Anke Kissinger, Henning Lausberg, Roland Fries, Hans-Joachim Schäfers.   

Abstract

OBJECTIVES: Aortic dilatation occurs in many patients with bicuspid aortic valves. We have added root replacement using the remodeling technique originally designed for tricuspid aortic valves to bicuspid aortic valve repair for treatment of the dilated root. We compared the results of remodeling in bicuspid aortic valves with those in tricuspid aortic valves.
METHODS: From October 1995 through January 2004, 60 patients underwent root remodeling for bicuspid aortic valves (group A), and 130 patients underwent root remodeling for tricuspid aortic valves (group B). Correction of cusp prolapse was more often performed in group A (group A, 50/60; group B, 47/130; P < .0001). Transthoracic echocardiography was performed at 1 week, 6 and 12 months, and every year thereafter. Cumulative follow-up was 527 patient-years (mean, 2.9 +/- 2 years).
RESULTS: No patient died in group A. Hospital mortality in group B was 5% (5/100; 95% confidence interval,1.6%-11.3%) after elective operations and 10% (3/30; 95% confidence interval, 2.1%-26.5%) after emergency operations. Mean systolic gradients were identical at 1 year (group A, 4.8 +/- 2.1 mm Hg; group B, 4.0 +/- 2 mm Hg) and 5 years (group A, 4.5 +/- 2.3 mm Hg; group B, 3.9 +/- 2.2 mm Hg). Freedom from aortic regurgitation of grade 2 or higher at 5 years was 96% in group A and 83% in group B ( P = .07), and freedom from reoperation at 5 years was 98% in group A and 98% in group B ( P = .73).
CONCLUSIONS: Valve-sparing aortic replacement with root remodeling can be applied to aortic dilatation and a regurgitant bicuspid aortic valve. Hemodynamic function and valve stability of a repaired bicuspid aortic valve are comparable with those seen in cases of tricuspid anatomy.

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Year:  2004        PMID: 15514592     DOI: 10.1016/j.jtcvs.2004.06.035

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  9 in total

1.  Reconstruction of bicuspid aortic valves. Surgical tool or toy?

Authors:  H-J Schäfers
Journal:  Z Kardiol       Date:  2005-07

2.  Root remodeling for aortic root dilatation.

Authors:  Hans-Joachim Schäfers; Diana Aicher
Journal:  Ann Cardiothorac Surg       Date:  2013-01

3.  Embolic and bleeding events after modified Bentall procedure in selected patients.

Authors:  N C Radu; E W M Kirsch; M-L Hillion; F Lagneau; L Drouet; D Loisance
Journal:  Heart       Date:  2006-06-27       Impact factor: 5.994

4.  Bicuspidy does not affect reoperation risk following aortic valve reimplantation.

Authors:  Pietro Giorgio Malvindi; Giuseppe Maria Raffa; Alessio Basciu; Enrico Citterio; Antioco Cappai; Diego Ornaghi; Giuseppe Tarelli; Fabrizio Settepani
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-03-02

5.  Approach to the patient with bicuspid aortic valve and ascending aorta aneurysm.

Authors:  José T Ortiz; David D Shin; Nalini M Rajamannan
Journal:  Curr Treat Options Cardiovasc Med       Date:  2006-12

6.  Aortic root remodeling in bicuspid and tricuspid aortic valves-long-term results.

Authors:  Shunsuke Miyahara; Irem Karliova; Christian Giebels; Ulrich Schneider; Shunsuke Matsushima; Hans-Joachim Schäfers
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2019-02-15

7.  Pathophysiological implications of different bicuspid aortic valve configurations.

Authors:  F A Kari; F Beyersdorf; M Siepe
Journal:  Cardiol Res Pract       Date:  2012-05-27       Impact factor: 1.866

8.  Quantitative analysis of 3-dimensional aortic annular geometry: implication for aortic root reimplantation.

Authors:  Liam P Ryan; Melissa M Levack; Joseph H Gorman; Robert C Gorman; Rita C Milewski; Joseph E Bavaria
Journal:  J Thorac Cardiovasc Surg       Date:  2013-12-09       Impact factor: 6.439

9.  Bicuspid aortic valve repair in the setting of severe aortic insufficiency.

Authors:  Ziv Beckerman; Michael O Kayatta; LaRonica McPherson; Jose N Binongo; Yi Lasanajak; Bradley G Leshnower; Edward P Chen
Journal:  J Vis Surg       Date:  2018-05-14
  9 in total

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