Literature DB >> 15514077

Genes encoding vitamin-K epoxide reductase are present in Drosophila and trypanosomatid protists.

Hugh M Robertson1.   

Abstract

Vitamin-K epoxide reductase is encoded by the VKORC1 gene in mammals and other vertebrates, which also have a paralog, VKORC1L1. Single homologs are present in basal deuterostome and insect genomes, including Drosophila, and three trypanosomatid protists. VKOR is therefore an ancient gene/protein that can be studied in the Drosophila model system.

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Year:  2004        PMID： 15514077      PMCID： PMC1448852          DOI： 10.1534/genetics.104.029744

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  17 in total

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Journal:  Science       Date:  2002-10-04       Impact factor: 47.728

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8.  Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing.

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Journal:  Nature       Date:  2003-04-24       Impact factor: 49.962

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Journal:  Genome Biol       Date:  2002-12-31       Impact factor: 13.583

10.  An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome.

Authors:  M Hild; B Beckmann; S A Haas; B Koch; V Solovyev; C Busold; K Fellenberg; M Boutros; M Vingron; F Sauer; J D Hoheisel; R Paro
Journal:  Genome Biol       Date:  2003-12-22       Impact factor: 13.583
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  7 in total

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Review 2.  Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis.

Authors:  Martin J Shearer; Paul Newman
Journal:  J Lipid Res       Date:  2014-01-31       Impact factor: 5.922

3.  GGCX and VKORC1 inhibit osteocalcin endocrine functions.

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Review 4.  VKORC1L1, An Enzyme Mediating the Effect of Vitamin K in Liver and Extrahepatic Tissues.

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Review 5.  Structural Modeling Insights into Human VKORC1 Phenotypes.

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6.  Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family.

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