Literature DB >> 15513409

Impact of prolonged treatment with trimethoprim-sulfamethoxazole on the human gut flora.

Diamantis P Kofteridis1, Sofia Maraki, Ioanna Mixaki, Elpis Mantadakis, George Samonis.   

Abstract

The case of a mentally ill man inadvertently treated with trimethoprim-sulfamethoxazole (TMP-SMX) for 2 y is presented. Quantitative stool cultures revealed a substantially suppressed Gram-negative aerobic flora, while Enterococcus spp. and anaerobes were not affected. Yeasts were moderately increased. TMP-SMX represents an attractive antimicrobial for immunocompromized patients who need the integrity of their intestinal anaerobic flora for colonization resistance.

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Year:  2004        PMID: 15513409     DOI: 10.1080/00365540410020956

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN: 0036-5548


  3 in total

Review 1.  Cancer chemotherapy-induced diarrhoea and constipation: mechanisms of damage and prevention strategies.

Authors:  Rachel J Gibson; Dorothy M K Keefe
Journal:  Support Care Cancer       Date:  2006-04-08       Impact factor: 3.603

2.  Non-antibiotic Small-Molecule Regulation of DHFR-Based Destabilizing Domains In Vivo.

Authors:  Hui Peng; Viet Q Chau; Wanida Phetsang; Rebecca M Sebastian; M Rhia L Stone; Shyamtanu Datta; Marian Renwick; Yusuf T Tamer; Erdal Toprak; Andrew Y Koh; Mark A T Blaskovich; John D Hulleman
Journal:  Mol Ther Methods Clin Dev       Date:  2019-08-15       Impact factor: 6.698

3.  Development of an in vitro Model of Human Gut Microbiota for Screening the Reciprocal Interactions With Antibiotics, Drugs, and Xenobiotics.

Authors:  Abdelaziz El Houari; Florine Ecale; Anne Mercier; Stéphanie Crapart; Jérôme Laparre; Baptiste Soulard; Manilduth Ramnath; Jean-Marc Berjeaud; Marie-Hélène Rodier; Alexandre Crépin
Journal:  Front Microbiol       Date:  2022-04-12       Impact factor: 6.064

  3 in total

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