Literature DB >> 15510160

Post-translational modification of p53 in tumorigenesis.

Ann M Bode1, Zigang Dong.   

Abstract

Interest in the tumour suppressor p53 has generated much information regarding the complexity of its function and regulation in carcinogenesis. However, gaps still exist in our knowledge regarding the role of p53 post-translational modifications in carcinogenesis and cancer prevention. A thorough understanding of p53 will be extremely useful in the development of new strategies for treating and preventing cancer, including restoration of p53 function and selective killing of tumours with mutant TP53.

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Year:  2004        PMID： 15510160     DOI： 10.1038/nrc1455

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  456 in total

Review 1.  MicroRNAs, wild-type and mutant p53: more questions than answers.

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Review 2.  Chemopreventive potential of natural compounds in head and neck cancer.

Authors:  Mohammad Aminur Rahman; A R M Ruhul Amin; Dong M Shin
Journal:  Nutr Cancer       Date:  2010       Impact factor: 2.900

3.  Operating on chromatin, a colorful language where context matters.

Authors:  Kathryn E Gardner; C David Allis; Brian D Strahl
Journal:  J Mol Biol       Date:  2011-01-25       Impact factor: 5.469

4.  Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells.

Authors:  Wendell S Fortson; Shubhalaxmi Kayarthodi; Yasuo Fujimura; Huali Xu; Roland Matthews; William E Grizzle; Veena N Rao; Ganapathy K Bhat; E Shyam P Reddy
Journal:  Int J Oncol       Date:  2011-04-21       Impact factor: 5.650

5.  Mechanisms of p53 activation and physiological relevance in the developing kidney.

Authors:  Karam Aboudehen; Sylvia Hilliard; Zubaida Saifudeen; Samir S El-Dahr
Journal:  Am J Physiol Renal Physiol       Date:  2012-01-11

6.  Coordination between cell cycle progression and cell fate decision by the p53 and E2F1 pathways in response to DNA damage.

Authors:  Xiao-Peng Zhang; Feng Liu; Wei Wang
Journal:  J Biol Chem       Date:  2010-08-04       Impact factor: 5.157

Review 7.  Posttranslational modification of p53: cooperative integrators of function.

Authors:  David W Meek; Carl W Anderson
Journal:  Cold Spring Harb Perspect Biol       Date:  2009-10-28       Impact factor: 10.005

8.  Phosphorylation of p53 by TAF1 inactivates p53-dependent transcription in the DNA damage response.

Authors:  Yong Wu; Joy C Lin; Landon G Piluso; Joseph M Dhahbi; Selene Bobadilla; Stephen R Spindler; Xuan Liu
Journal:  Mol Cell       Date:  2013-11-27       Impact factor: 17.970

9.  Regulation of the cyclin-dependent kinase inhibitor 1A gene (CDKN1A) by the repressor BOZF1 through inhibition of p53 acetylation and transcription factor Sp1 binding.

Authors:  Min-Kyeong Kim; Bu-Nam Jeon; Dong-In Koh; Kyung-Sup Kim; So-Yoon Park; Chae-Ok Yun; Man-Wook Hur
Journal:  J Biol Chem       Date:  2013-01-17       Impact factor: 5.157

10.  The baculovirus sulfhydryl oxidase Ac92 (P33) interacts with the Spodoptera frugiperda P53 protein and oxidizes it in vitro.

Authors:  Wenbi Wu; Rollie J Clem; George F Rohrmann; A Lorena Passarelli
Journal:  Virology       Date:  2013-10-01       Impact factor: 3.616
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