Literature DB >> 1550995

Random genetic drift and selection in a triallelic locus: a continuous diffusion model.

H G Spencer1, R Barakat.   

Abstract

The Kolmogorov forward diffusion equation is used to examine the evolution of three alleles at one locus under viability selection and random genetic drift. Separation of variables and Chebyschev approximations are employed to solve this equation for long times. As an example, one artificial viability set is examined in detail; its general implications for the evolution at a triallelic locus are discussed.

Mesh:

Year:  1992        PMID: 1550995     DOI: 10.1016/0025-5564(92)90008-k

Source DB:  PubMed          Journal:  Math Biosci        ISSN: 0025-5564            Impact factor:   2.144


  1 in total

1.  Triallelic Population Genomics for Inferring Correlated Fitness Effects of Same Site Nonsynonymous Mutations.

Authors:  Aaron P Ragsdale; Alec J Coffman; PingHsun Hsieh; Travis J Struck; Ryan N Gutenkunst
Journal:  Genetics       Date:  2016-03-30       Impact factor: 4.562

  1 in total

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