Literature DB >> 15509670

My approach to atypical melanocytic lesions.

K S Culpepper1, S R Granter, P H McKee.   

Abstract

Histological assessment of melanocytic naevi constitutes a substantial proportion of a dermatopathologist's daily workload. Although they may be excised for cosmetic reasons, most lesions encountered are clinically atypical and are biopsied or excised to exclude melanoma. Although dysplastic naevi are most often encountered, cytological atypia may be a feature of several other melanocytic lesions, including genital type naevi, acral naevi, recurrent naevi, and neonatal or childhood naevi. With greater emphasis being given to cosmetic results, and because of an ever increasing workload, several "quicker and less traumatising" techniques have been introduced in the treatment and diagnosis of atypical naevi including punch, shave, and scoop shave biopsies. A major limitation to all of these alternatives is that often only part of the lesion is available for histological assessment and therefore all too frequently the pathologist's report includes a recommendation for complete excision so that the residual lesion can be studied. Complete or large excision of all clinically atypical naevi permits histological assessment of the entire lesion, and in most cases spares the patient the need for further surgical intervention.

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Year:  2004        PMID: 15509670      PMCID: PMC1770470          DOI: 10.1136/jcp.2003.008516

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  45 in total

1.  Pagetoid variant of actinic keratosis with or without squamous cell carcinoma of sun-exposed skin: a lesion simulating extramammary Paget's disease.

Authors:  K T Mai; T Alhalouly; D Landry; W A Stinson; D G Perkins; H M Yazdi
Journal:  Histopathology       Date:  2002-10       Impact factor: 5.087

2.  Melanoma incidence and mortality among US whites, 1969-1999.

Authors:  Alan C Geller; Donald R Miller; George David Annas; Marie-France Demierre; Barbara A Gilchrest; Howard K Koh
Journal:  JAMA       Date:  2002-10-09       Impact factor: 56.272

3.  Sentinel lymph node biopsy in patients with diagnostically controversial spitzoid melanocytic tumors.

Authors:  Christina M Lohmann; Daniel G Coit; Mary S Brady; Marianne Berwick; Klaus J Busam
Journal:  Am J Surg Pathol       Date:  2002-01       Impact factor: 6.394

4.  Spindle and epithelioid cell nevi in children and adults. A review of 211 cases of the Spitz nevus.

Authors:  D Weedon; J H Little
Journal:  Cancer       Date:  1977-07       Impact factor: 6.860

5.  Analysis of heterogeneity of atypia within melanocytic nevi.

Authors:  Ronald J Barr; Kenneth G Linden; Gennady Rubinstein; Kenneth A Cantos
Journal:  Arch Dermatol       Date:  2003-03

Review 6.  Clear cell papulosis (pagetoid papulosis) in a non-Asian patient.

Authors:  R Gianotti; S Cambiaghi; A Locatelli; C Gelmetti
Journal:  Dermatology       Date:  2001       Impact factor: 5.366

7.  Melanoma resembling spindle and epithelioid cell nevus.

Authors:  M R Okun
Journal:  Arch Dermatol       Date:  1979-12

8.  Melanomas in prepubescent children: review comprehensively, critique historically, criteria diagnostically, and course biologically.

Authors:  Joan M Mones; A Bernard Ackerman
Journal:  Am J Dermatopathol       Date:  2003-06       Impact factor: 1.533

9.  Sentinel lymph node biopsy for patients with problematic spitzoid melanocytic lesions: a report on 18 patients.

Authors:  Lyndon D Su; Douglas R Fullen; Vernon K Sondak; Timothy M Johnson; Lori Lowe
Journal:  Cancer       Date:  2003-01-15       Impact factor: 6.860

10.  A natural history of melanomas and dysplastic nevi: an atlas of lesions in melanoma-prone families.

Authors:  Margaret A Tucker; Mary C Fraser; Alisa M Goldstein; Jeffery P Struewing; Mary A King; John T Crawford; Ellen A Chiazze; Deborah P Zametkin; Laura S Fontaine; Wallace H Clark
Journal:  Cancer       Date:  2002-06-15       Impact factor: 6.860

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  6 in total

1.  Distinguishing between benign and malignant melanocytic nevi by in vivo multiphoton microscopy.

Authors:  Mihaela Balu; Kristen M Kelly; Christopher B Zachary; Ronald M Harris; Tatiana B Krasieva; Karsten König; Anthony J Durkin; Bruce J Tromberg
Journal:  Cancer Res       Date:  2014-03-31       Impact factor: 12.701

2.  Image and statistical analysis of melanocytic histology.

Authors:  Jayson Miedema; James Stephen Marron; Marc Niethammer; David Borland; John Woosley; Jason Coposky; Susan Wei; Howard Reisner; Nancy E Thomas
Journal:  Histopathology       Date:  2012-06-11       Impact factor: 5.087

3.  [Melanocytic nevi at special anatomical sites].

Authors:  L Schärer
Journal:  Pathologe       Date:  2007-11       Impact factor: 1.011

4.  Low rates of clinical recurrence after biopsy of benign to moderately dysplastic melanocytic nevi.

Authors:  Agnessa Gadeliya Goodson; Scott R Florell; Kenneth M Boucher; Douglas Grossman
Journal:  J Am Acad Dermatol       Date:  2009-12-16       Impact factor: 11.527

Review 5.  Optimal management of common acquired melanocytic nevi (moles): current perspectives.

Authors:  Kabir Sardana; Payal Chakravarty; Khushbu Goel
Journal:  Clin Cosmet Investig Dermatol       Date:  2014-03-19

6.  Recurrence of Dysplastic Nevi Is Strongly Associated with Extension of the Lesions to the Lateral Margins and into the Deep Margins through the Hair Follicles in the Original Shave Removal Specimens.

Authors:  Amin Maghari
Journal:  Dermatol Res Pract       Date:  2016-09-28
  6 in total

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