Literature DB >> 15509136

Efficacy and tolerability of a combination of Lyprinol and high concentrations of EPA and DHA in inflammatory rheumatoid disorders.

Joerg Gruenwald1, Hans-Joachim Graubaum, Knuth Hansen, Barbara Grube.   

Abstract

This 12-week drug-monitoring study was conducted to evaluate the efficacy of Sanhelios Mussel Lyprinol Lipid Complex on 50 adult men and women with inflammatory rheumatoid arthritis. A total of 34 patients required drug therapy before and during the study. By the end of the study, 21 (62%) patients were able to reduce their dosage and 13 were able to terminate drug therapy. At the end of the treatment period, 38% were regarded symptom free, and the number of patients with severe pain decreased significantly from 60% at baseline to 25% at the completion of the trial. A significant effect was observed for each investigated parameter. The special combination of Lyprinol and omega-3 fatty acids was generally very well tolerated, with only one, nonserious adverse event (mild nausea) reported. This dietary supplement may therefore be considered an effective and well-tolerated component of treatment regimens for inflammatory rheumatoid arthritis.

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Year:  2004        PMID: 15509136     DOI: 10.1007/bf02850125

Source DB:  PubMed          Journal:  Adv Ther        ISSN: 0741-238X            Impact factor:   3.845


  6 in total

1.  Green lipped mussel oil complex suppresses lipopolysaccharide stimulated inflammation via regulating nuclear factor-κB and mitogen activated protein kinases signaling in RAW264.7 murine macrophages.

Authors:  Jing Chen; Cheng Bao; Se Haeng Cho; Hong Jin Lee
Journal:  Food Sci Biotechnol       Date:  2017-06-08       Impact factor: 2.391

2.  Sesame Oil and Rice Bran Oil Ameliorates Adjuvant-Induced Arthritis in Rats: Distinguishing the Role of Minor Components and Fatty Acids.

Authors:  Nayana Venugopal Yadav; Breetha Ramaiyan; Pooja Acharya; Lokesh Belur; Ramaprasad Ravichandra Talahalli
Journal:  Lipids       Date:  2016-10-17       Impact factor: 1.880

Review 3.  The Relationship between Fatty Acids and the Development, Course and Treatment of Rheumatoid Arthritis.

Authors:  Wojciech Tański; Natalia Świątoniowska-Lonc; Mateusz Tabin; Beata Jankowska-Polańska
Journal:  Nutrients       Date:  2022-02-28       Impact factor: 5.717

4.  Lyprinol-is it a useful anti-inflammatory agent?

Authors:  Sheila A Doggrell
Journal:  Evid Based Complement Alternat Med       Date:  2011-08-11       Impact factor: 2.629

5.  Pain Controlling and Cytokine-regulating Effects of Lyprinol, a Lipid Extract of Perna Canaliculus, in a Rat Adjuvant-induced Arthritis Model.

Authors:  Chi-Ho Lee; John Hon-Kei Lum; Curtise Kin-Cheung Ng; Janice McKay; Yoki Kwok-Chu Butt; Man-Sau Wong; Samuel Chun-Lap Lo
Journal:  Evid Based Complement Alternat Med       Date:  2007-09-26       Impact factor: 2.629

6.  Detailed distribution of lipids in Greenshell™ mussel (Perna canaliculus).

Authors:  Matthew R Miller; Luke Pearce; Bodhi I Bettjeman
Journal:  Nutrients       Date:  2014-04-11       Impact factor: 5.717

  6 in total

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