Is Gulf War Syndrome really a mystery?

Since the end of the 1991 Gulf War about 20,000 United States veterans and similar proportions of troops from other allied contingents have been affected by a variety of symptoms which have collectively become known as 'Gulf War Syndrome'. Similar symptoms have been reported in Iraqi civilians including children. Despite extensive investigations no agreement has been reached on whether there is an underlying cause or causes. In this article, the principal features of the illness are summarised and some of the proposed causes discussed. It is proposed that the common cause is the toxic smoke from incomplete combustion of oil from burning wells, and this hypothesis is related to the known toxicology of two likely combustion products, nitric oxide and carbon monoxide. The effect of this proposal on possible investigations and treatment is considered.