Literature DB >> 15508338

Preliminary studies on the biting activity and transmission of Onchocerca volvulus by Simulium neavei (diptera: simuliidae) in Kashoya-Kitomi focus, Western Uganda.

T L Lakwo1.   

Abstract

OBJECTIVE: To determine the biting activity and onchocerciasis transmission in Kashoya-Kitomi focus, Western Uganda.
DESIGN: Cross-sectional survey in randomly selected sites.
SETTING: Three districts in Western Uganda.
METHOD: Crab trapping and examination for immature stages of Simulium neavei and full day human bait catches and dissections were conducted at three sites.
RESULTS: A total of 338 crabs were caught and out of this 372 (95.9%) were positive with immature stages of S. neavei with mean S. neavei/crab of 6.9. High biting density of S. neavei was observed in the two sites in Kabarole and Mbarara districts whereas an extremely low density was observed at a site in Bushenyi. Diurnal biting pattern revealed two peaks in the morning (09:00-10:00 hours.) and in the late afternoon (14:00-15:00 hours.) with a mid-day lull. The infection/infective rates were 53.3/11.0%, 30.7% to 7.8% and 20.0/0% for sites in Mbarara, Kabarole and Bushenyi districts, respectively. Monthly biting rates/ Transmission potentials for Mbarara, Kabarole and Bushenyi districts were 6231/5437, 9244/2916 and 247/0.
CONCLUSION: There was high transmission of onchocerciasis observed in Kashoya-Kitomi focus despite the ongoing ivermectin treatment. The need for improved chemotherapeutic coverage and instituting other control measures may be necessary.

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Year:  2004        PMID: 15508338     DOI: 10.4314/eamj.v81i5.9167

Source DB:  PubMed          Journal:  East Afr Med J        ISSN: 0012-835X


  3 in total

1.  Serosurveillance to monitor onchocerciasis elimination: the Ugandan experience.

Authors:  David Oguttu; Edson Byamukama; Charles R Katholi; Peace Habomugisha; Christine Nahabwe; Monica Ngabirano; Hassan K Hassan; Thomson Lakwo; Moses Katabarwa; Frank O Richards; Thomas R Unnasch
Journal:  Am J Trop Med Hyg       Date:  2013-12-16       Impact factor: 2.345

2.  Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity.

Authors:  Stephen R Doyle; Catherine Bourguinat; Hugues C Nana-Djeunga; Jonas A Kengne-Ouafo; Sébastien D S Pion; Jean Bopda; Joseph Kamgno; Samuel Wanji; Hua Che; Annette C Kuesel; Martin Walker; Maria-Gloria Basáñez; Daniel A Boakye; Mike Y Osei-Atweneboana; Michel Boussinesq; Roger K Prichard; Warwick N Grant
Journal:  PLoS Negl Trop Dis       Date:  2017-07-26

3.  The Imaramagambo Onchocerciasis Focus in Southwestern Uganda: Interruption of Transmission After Disappearance of the Vector Simulium neavei and Its Associated Freshwater Crabs.

Authors:  Moses N Katabarwa; James Katamanywa; Thomson Lakwo; Peace Habomugisha; Edson Byamukama; David Oguttu; Christine Nahabwe; Monica Ngabirano; Ephraim Tukesiga; Annet Khainza; Edridah Tukahebwa; Thomas R Unnasch; Frank O Richards; Rolf Garms
Journal:  Am J Trop Med Hyg       Date:  2016-05-23       Impact factor: 2.345

  3 in total

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