Literature DB >> 15504892

Comparison of simultaneous splenic sample PCR with blood sample PCR for diagnosis and treatment of experimental Ehrlichia canis infection.

Shimon Harrus1, Martin Kenny, Limor Miara, Itzhak Aizenberg, Trevor Waner, Susan Shaw.   

Abstract

This report presents evidence that dogs recover from acute canine monocytic ehrlichiosis (CME) after 16 days of doxycycline treatment (10 mg/kg of body weight every 24 h). Blood PCR was as valuable as splenic aspirate PCR for early diagnosis of acute CME. Splenic aspirate PCR was, however, superior to blood PCR for the evaluation of ehrlichial elimination.

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Year:  2004        PMID： 15504892      PMCID： PMC525421          DOI： 10.1128/AAC.48.11.4488-4490.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

1.  Detection of Ehrlichia canis in canine carrier blood and in individual experimentally infected ticks with a p30-based PCR assay.

Authors:  Roger W Stich; Yasuko Rikihisa; S A Ewing; Glen R Needham; Debra L Grover; Sathaporn Jittapalapong
Journal:  J Clin Microbiol       Date:  2002-02       Impact factor: 5.948

2.  Laboratory studies of tropical canine pancytopenia.

Authors:  D L Huxsoll; H L Amyx; I E Hemelt; P K Hildebrandt; R M Nims; W S Gochenour
Journal:  Exp Parasitol       Date:  1972-02       Impact factor: 2.011

Review 3.  Consensus statement on ehrlichial disease of small animals from the infectious disease study group of the ACVIM. American College of Veterinary Internal Medicine.

Authors:  T Mark Neer; Edward B Breitschwerdt; Russell T Greene; Michael R Lappin
Journal:  J Vet Intern Med       Date:  2002 May-Jun       Impact factor: 3.333

Review 4.  Canine ehrlichiosis.

Authors:  Bogumila Skotarczak
Journal:  Ann Agric Environ Med       Date:  2003       Impact factor: 1.447

5.  Investigation of splenic functions in canine monocytic ehrlichiosis.

Authors:  S Harrus; T Waner; A Keysary; I Aroch; H Voet; H Bark
Journal:  Vet Immunol Immunopathol       Date:  1998-03-18       Impact factor: 2.046

6.  Reisolation of Ehrlichia canis from blood and tissues of dogs after doxycycline treatment.

Authors:  Z Iqbal; Y Rikihisa
Journal:  J Clin Microbiol       Date:  1994-07       Impact factor: 5.948

7.  Therapeutic effect of doxycycline in experimental subclinical canine monocytic ehrlichiosis: evaluation of a 6-week course.

Authors:  S Harrus; T Waner; I Aizenberg; H Bark
Journal:  J Clin Microbiol       Date:  1998-07       Impact factor: 5.948

8.  Demonstration of serum antiplatelet antibodies in experimental acute canine ehrlichiosis.

Authors:  T Waner; S Harrus; D J Weiss; H Bark; A Keysary
Journal:  Vet Immunol Immunopathol       Date:  1995-09       Impact factor: 2.046

9.  Tropical canine pancytopenia: Clinical, hematologic, and serologic response of dogs to Ehrlichia canis infection, tetracycline therapy, and challenge inoculation.

Authors:  W C Buhles; D L Huxsoll; M Ristic
Journal:  J Infect Dis       Date:  1974-10       Impact factor: 5.226

10.  Serologic diagnosis of human ehrlichiosis using two Ehrlichia canis isolates.

Authors:  J E Dawson; Y Rikihisa; S A Ewing; D B Fishbein
Journal:  J Infect Dis       Date:  1991-03       Impact factor: 5.226
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  17 in total

1.  Efficacy of a doxycycline treatment regimen initiated during three different phases of experimental ehrlichiosis.

Authors:  Jennifer C McClure; Michelle L Crothers; John J Schaefer; Patrick D Stanley; Glen R Needham; S A Ewing; Roger W Stich
Journal:  Antimicrob Agents Chemother       Date:  2010-10-04       Impact factor: 5.191

2.  Efficacy of combined therapy with liposome-encapsulated meglumine antimoniate and allopurinol in treatment of canine visceral leishmaniasis.

Authors:  Sydnei M da Silva; Izabela F G Amorim; Raul R Ribeiro; Erly G Azevedo; Cynthia Demicheli; Maria N Melo; Wagner L Tafuri; Nelder F Gontijo; Marilene S M Michalick; Frédéric Frézard
Journal:  Antimicrob Agents Chemother       Date:  2012-03-12       Impact factor: 5.191

3.  Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate.

Authors:  John J Schaefer; Glen R Needham; William G Bremer; Yasuko Rikihisa; S A Ewing; R W Stich
Journal:  Antimicrob Agents Chemother       Date:  2007-07-02       Impact factor: 5.191

Review 4.  Guideline for veterinary practitioners on canine ehrlichiosis and anaplasmosis in Europe.

Authors:  Ángel Sainz; Xavier Roura; Guadalupe Miró; Agustín Estrada-Peña; Barbara Kohn; Shimon Harrus; Laia Solano-Gallego
Journal:  Parasit Vectors       Date:  2015-02-04       Impact factor: 3.876

5.  Molecular detection of Ehrlichia spp. in blood samples of dogs in southern Iran using polymerase chain reaction.

Authors:  Noushin Derakhshandeh; Hassan Sharifiyazdi; Mohammad Abbaszadeh Hasiri
Journal:  Vet Res Forum       Date:  2017-12-15       Impact factor: 1.054

6.  Are vector-borne pathogen co-infections complicating the clinical presentation in dogs?

Authors:  Anna Sara De Tommasi; Domenico Otranto; Filipe Dantas-Torres; Gioia Capelli; Edward B Breitschwerdt; Donato de Caprariis
Journal:  Parasit Vectors       Date:  2013-04-15       Impact factor: 3.876

7.  Molecular detection of Ehrlichia canis in dogs in Malaysia.

Authors:  Mojgan Nazari; Sue Yee Lim; Mahira Watanabe; Reuben S K Sharma; Nadzariah A B Y Cheng; Malaika Watanabe
Journal:  PLoS Negl Trop Dis       Date:  2013-01-03

8.  Ehrlichiosis, babesiosis, anaplasmosis and hepatozoonosis in dogs from St. Kitts, West Indies.

Authors:  Patrick J Kelly; Chuanling Xu; Helene Lucas; Amanda Loftis; Jamie Abete; Frank Zeoli; Audrey Stevens; Kirsten Jaegersen; Kate Ackerson; April Gessner; Bernhard Kaltenboeck; Chengming Wang
Journal:  PLoS One       Date:  2013-01-15       Impact factor: 3.240

9.  Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat.

Authors:  C M Bhadesiya; S K Raval
Journal:  Vet World       Date:  2015-06-06

10.  Efficacy of Minocycline in Naturally Occurring Nonacute Ehrlichia canis Infection in Dogs.

Authors:  S Jenkins; J K Ketzis; J Dundas; D Scorpio
Journal:  J Vet Intern Med       Date:  2017-12-02       Impact factor: 3.333
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