Superior mediastinal syndrome with Rowland-Payne syndrome: an unusual presentation of cervico-mediastinal neuroblastoma.

A 5-month-old boy presented with superior mediastinal syndrome due to a large, unresectable cervico-mediastinal neuroblastoma. He had an unusual constellation of findings not previously reported in neuroblastoma: Horner syndrome, phrenic nerve palsy, and palsy of the ipsilateral recurrent laryngeal nerve. This constellation of findings in adult malignancies is termed the Rowland-Payne syndrome. The child required prolonged mechanical ventilation but responded to chemotherapy and is now free of tumor and completely recovered. (c) 2004 Wiley-Liss, Inc.