Literature DB >> 15501200

Misdiagnosis of atrial fibrillation and its clinical consequences.

Frank Bogun1, Daejoon Anh, Gautham Kalahasty, Erik Wissner, Chadi Bou Serhal, Rabih Bazzi, W Douglas Weaver, Claudio Schuger.   

Abstract

PURPOSE: Computer algorithms are often used for cardiac rhythm interpretation and are subsequently corrected by an overreading physician. The purpose of this study was to assess the incidence and clinical consequences of misdiagnosis of atrial fibrillation based on a 12-lead electrocardiogram (ECG).
METHODS: We retrieved 2298 ECGs with the computerized interpretation of atrial fibrillation from 1085 patients. The ECGs were reinterpreted to determine the accuracy of the interpretation. In patients in whom the interpretation was incorrect, we reviewed the medical records to assess the clinical consequences resulting from misdiagnosis.
RESULTS: We found that 442 ECGs (19%) from 382 (35%) of the 1085 patients had been incorrectly interpreted as atrial fibrillation by the computer algorithm. In 92 patients (24%), the physician ordering the ECG had failed to correct the inaccurate interpretation, resulting in change in management and initiation of inappropriate treatment, including antiarrhythmic medications and anticoagulation in 39 patients (10%), as well as unnecessary additional diagnostic testing in 90 patients (24%). A final diagnosis of paroxysmal atrial fibrillation based on the initial incorrect interpretation of the ECGs was generated in 43 patients (11%).
CONCLUSION: Incorrect computerized interpretation of atrial fibrillation, combined with the failure of the ordering physician to correct the erroneous interpretation, can result in the initiation of unnecessary, potentially harmful medical treatment as well as inappropriate use of medical resources. Greater efforts should be directed toward educating physicians about the electrocardiographic appearance of atrial dysrhythmias and in the recognition of confounding artifacts.

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Year:  2004        PMID: 15501200     DOI: 10.1016/j.amjmed.2004.06.024

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  23 in total

Review 1.  Wearing Your Heart on Your Sleeve: the Future of Cardiac Rhythm Monitoring.

Authors:  Mostafa A Al-Alusi; Eric Ding; David D McManus; Steven A Lubitz
Journal:  Curr Cardiol Rep       Date:  2019-11-25       Impact factor: 2.931

Review 2.  Identification, diagnosis and assessment of atrial fibrillation.

Authors:  R I Dewar; G Y H Lip
Journal:  Heart       Date:  2006-09-04       Impact factor: 5.994

Review 3.  Automation bias: a systematic review of frequency, effect mediators, and mitigators.

Authors:  Kate Goddard; Abdul Roudsari; Jeremy C Wyatt
Journal:  J Am Med Inform Assoc       Date:  2011-06-16       Impact factor: 4.497

4.  Accurate ECG diagnosis of atrial tachyarrhythmias using quantitative analysis: a prospective diagnostic and cost-effectiveness study.

Authors:  David E Krummen; Mitul Patel; Hong Nguyen; Gordon Ho; Dhruv S Kazi; Paul Clopton; Marian C Holland; Scott L Greenberg; Gregory K Feld; Mitchell N Faddis; Sanjiv M Narayan
Journal:  J Cardiovasc Electrophysiol       Date:  2010-11

5.  Patient selection for ambulatory cardiac monitoring in the Indian healthcare environment.

Authors:  Maneesh Shrivastav; Rajendra Shrivastav; Jitendra Makkar; Mauro Biffi
Journal:  Heart Asia       Date:  2013-01-27

6.  Rhythmic chaos: irregularities of computer ECG diagnosis.

Authors:  Yi-Ting Laureen Wang; Swee-Chong Seow; Devinder Singh; Kian-Keong Poh; Ping Chai
Journal:  Singapore Med J       Date:  2017-09       Impact factor: 1.858

7.  Socioeconomic status and the development of atrial fibrillation in Hispanics, African Americans and non-Hispanic whites.

Authors:  Eric Shulman; Faraj Kargoli; Philip Aagaard; Ethan Hoch; Luigi Di Biase; John Fisher; Jay Gross; Soo Kim; Kevin J Ferrick; Andrew Krumerman
Journal:  Clin Cardiol       Date:  2017-06-09       Impact factor: 2.882

8.  Development and validation of diagnostic criteria for atrial flutter on the surface electrocardiogram.

Authors:  Kenneth M Weinberg; Pablo Denes; Alan H Kadish; Jeffrey J Goldberger
Journal:  Ann Noninvasive Electrocardiol       Date:  2008-04       Impact factor: 1.468

9.  Determining the clinical significance of computer interpreted electrocardiography conclusions.

Authors:  Daniel J Kersten; Kyla D'Angelo; Juana Vargas; Gagan Verma; Uzma Malik; Schlomo Shavolian; Roman Zeltser; Ofek Hai; Amgad N Makaryus
Journal:  Am J Cardiovasc Dis       Date:  2021-06-15

Review 10.  Automation bias and verification complexity: a systematic review.

Authors:  David Lyell; Enrico Coiera
Journal:  J Am Med Inform Assoc       Date:  2017-03-01       Impact factor: 4.497

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