Literature DB >> 15501064

Synthesis and inhibitory effects of pinosylvin derivatives on prostaglandin E2 production in lipopolysaccharide-induced mouse macrophage cells.

Eun-Jung Park1, Hye-Young Min, Yong-Hyun Ahn, Cheol-Man Bae, Jae-Ho Pyee, Sang Kook Lee.   

Abstract

A series of natural stilbenoids, pinosylvin and its derivatives, were synthesized and evaluated for the inhibitory activity of prostaglandin E(2) production in lipopolysaccharide-induced RAW 264.7 cells. Potential inhibitors, including 3,5-dimethoxy-trans-stilbene and 3-hydroxy-5-benzyloxy-trans-stilbene, have been newly identified, and thus providing chemical leads for the further development of anti-inflammatory or cancer chemopreventive agents.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15501064     DOI： 10.1016/j.bmcl.2004.09.022

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

Review 1.  Natural Sources and Pharmacological Properties of Pinosylvin.

Authors:  Saad Bakrim; Hamza Machate; Taoufiq Benali; Nargis Sahib; Imane Jaouadi; Nasreddine El Omari; Sara Aboulaghras; Sneh Punia Bangar; José Manuel Lorenzo; Gokhan Zengin; Domenico Montesano; Monica Gallo; Abdelhakim Bouyahya
Journal:  Plants (Basel)       Date:  2022-06-09

2.  The natural stilbenoid pinosylvin and activated neutrophils: effects on oxidative burst, protein kinase C, apoptosis and efficiency in adjuvant arthritis.

Authors:  Viera Jančinová; Tomáš Perečko; Rado Nosáľ; Juraj Harmatha; Jan Smidrkal; Katarína Drábiková
Journal:  Acta Pharmacol Sin       Date:  2012-07-30       Impact factor: 6.150

3.  Immobilization of laccase for oxidative coupling of trans-resveratrol and its derivatives.

Authors:  Hong Zhang; Erna Xun; Jiaxin Wang; Ge Chen; Tiexin Cheng; Zhi Wang; Tengfei Ji; Lei Wang
Journal:  Int J Mol Sci       Date:  2012-05-18       Impact factor: 6.208

4.  Anti-inflammatory activity of the ethanol extract of Dictamnus dasycarpus leaf in lipopolysaccharide-activated macrophages.

Authors:  Chiranjit Ghosh; Bora Hong; Subhasis Batabyal; Tae-Il Jeon; Seung-Hak Yang; Seong Gu Hwang
Journal:  BMC Complement Altern Med       Date:  2014-09-03       Impact factor: 3.659

Review 5.  Role of Natural Stilbenes in the Prevention of Cancer.

Authors:  J Antoni Sirerol; María L Rodríguez; Salvador Mena; Miguel A Asensi; José M Estrela; Angel L Ortega
Journal:  Oxid Med Cell Longev       Date:  2015-12-21       Impact factor: 6.543

6.  New classes of Gram-positive selective antibacterials: inhibitors of MRSA and surrogates of the causative agents of anthrax and tuberculosis.

Authors:  M Shahjahan Kabir; Kathleen Engelbrecht; Rebecca Polanowski; Sarah M Krueger; Rachel Ignasiak; Marc Rott; William R Schwan; Mary E Stemper; Kurt D Reed; David Sherman; James M Cook; Aaron Monte
Journal:  Bioorg Med Chem Lett       Date:  2008-09-26       Impact factor: 2.823
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.