| Literature DB >> 15500993 |
Lina Shalak1, Jeffrey M Perlman.
Abstract
An enhanced understanding of the cellular characteristics contributing to ongoing brain injury following intrapartum hypoxia-ischemia has resulted in the implementation of targeted neuroprotective strategies in the newborn period. This review briefly covers the pathogenesis of hypoxic-ischemic injury with an emphasis on reperfusion injury; the role of magnetic resonance imaging in the detection of such injury, and focuses on potential strategies both supportive and neuroprotective to prevent ongoing injury with a specific emphasis on modest hypothermia.Entities:
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Year: 2004 PMID： 15500993 DOI： 10.1016/j.earlhumdev.2004.06.003
Source DB: PubMed Journal: Early Hum Dev ISSN： 0378-3782 Impact factor: 2.079