Literature DB >> 15500420

The safety of black cohosh (Actaea racemosa, Cimicifuga racemosa).

Alyson Huntley1.   

Abstract

Black cohosh (Actaea racemosa/Cimicifuga racemosa) is a North American perennial plant that has been used for traditional medicinal purposes by the native Indian population. Its modern day application is the treatment of menopausal symptoms. Unlike conventional non-herbal medications, herbal preparations have not been systematically evaluated for their safety. However, the evidence from in vitro, animal and clinical studies all suggest that black cohosh is a safe herbal therapy for menopausal women if taken for a limited period. More research is needed to evaluate the safety of this herb over longer periods of time, and also to further investigate its mechanism of action.

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Year:  2004        PMID: 15500420     DOI: 10.1517/14740338.3.6.615

Source DB:  PubMed          Journal:  Expert Opin Drug Saf        ISSN: 1474-0338            Impact factor:   4.250


  8 in total

Review 1.  Pharmacological and non-hormonal treatment of hot flashes in breast cancer survivors: CEPO review and recommendations.

Authors:  Sylvain L'Espérance; Suzanne Frenette; Anne Dionne; Jean-Yves Dionne
Journal:  Support Care Cancer       Date:  2013-02-23       Impact factor: 3.603

2.  The first multicenter and randomized clinical trial of herbal Fufang for treatment of postmenopausal osteoporosis.

Authors:  H M Zhu; L Qin; P Garnero; H K Genant; G Zhang; K Dai; X Yao; G Gu; Y Hao; Z Li; Y Zhao; W Li; J Yang; X Zhao; D Shi; T Fuerst; Y Lu; H Li; X Zhang; C Li; J Zhao; Q Wu; S J Zhao
Journal:  Osteoporos Int       Date:  2011-04-20       Impact factor: 4.507

Review 3.  Ethnobotany, Phytochemistry, Traditional and Modern Uses of Actaea racemosa L. (Black cohosh): A Review.

Authors:  Sofia Salari; Mohammad Sadegh Amiri; Mahin Ramezani; Ali Tafazoli Moghadam; Sepideh Elyasi; Amirhossein Sahebkar; Seyed Ahmad Emami
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

4.  A Preliminary Study on the Effects of Black Cohosh Preparations on Bone Metabolism of Rat Models With GnRH-a-Induced Peri-Menopausal Symptoms.

Authors:  Zhenyue Qin; Zhiyong Dong; Junling Liu; Ahong Zhong; Mingyue Bao; Huihui Wang; Hongxia Yu; Shoufeng Zhang; Wendi Zhang; Li Shen; Jie Wu; Jiming Chen
Journal:  Front Endocrinol (Lausanne)       Date:  2022-06-09       Impact factor: 6.055

Review 5.  Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements.

Authors:  Lily Dara; Jennifer Hewett; Joseph Kartaik Lim
Journal:  World J Gastroenterol       Date:  2008-12-07       Impact factor: 5.742

6.  High-content screening and mechanism-based evaluation of estrogenic botanical extracts.

Authors:  Cassia R Overk; Ping Yao; Shaonong Chen; Shixing Deng; Ayano Imai; Matthew Main; Andreas Schinkovitz; Norman R Farnsworth; Guido F Pauli; Judy L Bolton
Journal:  Comb Chem High Throughput Screen       Date:  2008-05       Impact factor: 1.339

7.  Black Cohosh: Insights into its Mechanism(s) of Action.

Authors:  Rachel L Ruhlen; Grace Y Sun; Edward R Sauter
Journal:  Integr Med Insights       Date:  2008-08-27

8.  Litsea japonica Leaf Extract Suppresses Proinflammatory Cytokine Production in Periodontal Ligament Fibroblasts Stimulated with Oral Pathogenic Bacteria or Interleukin-1β.

Authors:  In-Gyeong Yun; Sun-Hee Ahn; Weon-Jong Yoon; Chang Sook Kim; Yun Kyong Lim; Joong-Ki Kook; Seunggon Jung; Choong-Ho Choi; Tae-Hoon Lee
Journal:  Int J Mol Sci       Date:  2018-08-23       Impact factor: 5.923

  8 in total

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