Literature DB >> 15500077

Effect of lauric acid on transdermal penetration of phenazepam in vivo.

I A Kravchenko1, N Ya Golovenko, V B Larionov, A I Aleksandrova, N V Ovcharenko.   

Abstract

We studied the effect of lauric acid on transdermal penetration of phenazepam in vivo. It was found that treatment with lauric acid 3-fold increased the maximum anticonvulsive effect of phenazepam applied in a transdermal therapeutic system in comparison with the control. Study of the pharmacokinetics of phenazepam transdermal therapeutic system showed its higher bioavailability in the presence of lauric acid (f=0.9).

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Year:  2003        PMID： 15500077     DOI： 10.1023/b:bebm.0000020209.13310.40

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  3 in total

1.  Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris.

Authors:  Teruaki Nakatsuji; Mandy C Kao; Jia-You Fang; Christos C Zouboulis; Liangfang Zhang; Richard L Gallo; Chun-Ming Huang
Journal:  J Invest Dermatol       Date:  2009-04-23       Impact factor: 8.551

2.  Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus.

Authors:  Andrew P Desbois; Keelan C Lawlor
Journal:  Mar Drugs       Date:  2013-11-13       Impact factor: 5.118

3.  Fostering Lavender as a Source for Valuable Bioactives for Food and Pharmaceutical Applications through Extraction and Microencapsulation.

Authors:  Simona Daniela Radu Lupoae; Liliana Mihalcea; Iuliana Aprodu; Sonia A Socaci; Mihaela Cotârleț; Elena Enachi; Oana Crăciunescu; Vasilica Barbu; Anca Oancea; Francisc Vasile Dulf; Petru Alexe; Gabriela Elena Bahrim; Gabriela Râpeanu; Nicoleta Stănciuc
Journal:  Molecules       Date:  2020-10-28       Impact factor: 4.411
  3 in total

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