P Roy1, D Kumar. 1. Department of Colorectal Surgery, St George's Hospital, Blackshaw Road, London SW17 0QT, UK.
Abstract
BACKGROUND: Advances in the use of bowel-sparing surgery for Crohn's disease have led to the development of strictureplasty as an important technique to conserve small bowel length and reduce morbidity associated with malabsorption. METHODS: A literature review of long-term studies on strictureplasty was undertaken, and evidence of its safety and efficacy was evaluated. RESULTS: The safety and efficacy of strictureplasty is confirmed in retrospective studies carried out over a period of 5-10 years, particularly when employed in patients at risk of short bowel syndrome, but certain questions regarding bowel function and disease activity after surgery remain unanswered. There is also concern that diseased tissue is left in situ after strictureplasty; this tissue has the potential for malignant transformation in the long term. CONCLUSION: Strictureplasty has been used in surgery for Crohn's disease for the past 25 years. Studies have proven its efficacy in the treatment of carefully selected patients at risk of malabsorption owing to short bowel syndrome. Copyright (c) 2004 British Journal of Surgery Society Ltd
BACKGROUND: Advances in the use of bowel-sparing surgery for Crohn's disease have led to the development of strictureplasty as an important technique to conserve small bowel length and reduce morbidity associated with malabsorption. METHODS: A literature review of long-term studies on strictureplasty was undertaken, and evidence of its safety and efficacy was evaluated. RESULTS: The safety and efficacy of strictureplasty is confirmed in retrospective studies carried out over a period of 5-10 years, particularly when employed in patients at risk of short bowel syndrome, but certain questions regarding bowel function and disease activity after surgery remain unanswered. There is also concern that diseased tissue is left in situ after strictureplasty; this tissue has the potential for malignant transformation in the long term. CONCLUSION: Strictureplasty has been used in surgery for Crohn's disease for the past 25 years. Studies have proven its efficacy in the treatment of carefully selected patients at risk of malabsorption owing to short bowel syndrome. Copyright (c) 2004 British Journal of Surgery Society Ltd
Authors: Jörg C Hoffmann; Frank Heller; Siegbert Faiss; Bernd von Lampe; Anton J Kroesen; Ulrich Wahnschaffe; Jörg-Dieter Schulzke; Martin Zeitz; Christian Bojarski Journal: Int J Colorectal Dis Date: 2008-03-13 Impact factor: 2.571
Authors: Christopher Andrew Lamb; Nicholas A Kennedy; Tim Raine; Philip Anthony Hendy; Philip J Smith; Jimmy K Limdi; Bu'Hussain Hayee; Miranda C E Lomer; Gareth C Parkes; Christian Selinger; Kevin J Barrett; R Justin Davies; Cathy Bennett; Stuart Gittens; Malcolm G Dunlop; Omar Faiz; Aileen Fraser; Vikki Garrick; Paul D Johnston; Miles Parkes; Jeremy Sanderson; Helen Terry; Daniel R Gaya; Tariq H Iqbal; Stuart A Taylor; Melissa Smith; Matthew Brookes; Richard Hansen; A Barney Hawthorne Journal: Gut Date: 2019-09-27 Impact factor: 23.059