Literature DB >> 15499476

[Prevalence of micro and macroangiopatic chronic complications and their risk factors in the care of out patients with type 2 diabetes mellitus].

Rafael Selbach Scheffel1, Desirê Bortolanza, Cristiane Seganfredo Weber, Luciana Abarno da Costa, Luís Henrique Canani, Kátia Gonçalves dos Santos, Daisy Crispim, Israel Roisenberg, Hugo Roberto Kurtz Lisbôa, Glaucia Sarturi Tres, Balduíno Tschiedel, Jorge Luiz Gross.   

Abstract

BACKGROUND: Type 2 diabetes (DM2) has been related to the development of macroangiopatic [coronary heart disease (CHD), peripheral vascular disease (PVD) and stroke] and microangiopatic [retinopathy, nephropathy, and distal sensory neuropathy (DSN)] complications. The aims of this study were to analyze prevalence of complications in DM2 patients and to estimate their associated risk factors.
METHODS: Cross-sectional study, including 927 out patients with DM2 from three medical centers in Rio Grande do Sul: Hospital de Clinicas de Porto Alegre (n = 475), Grupo Hospitalar Conceicao (n = 229) and Hospital Sao Vicente de Paula (n = 223). Of the patients 42% were male, mean age was 59 +/- 10 years and the median known duration of DM2 was 11 (5-43) years. Retinopathy was identified by direct fundoscopy; CHD by WHO questionnaire and/or abnormal ECG and/or perfusion abnormalities on myocardial scintigraphy; DSN by compatible symptoms and absent sensation on 10 g monofilament and/or tune fork; PVD by the presence of claudication and absent foot pulses; stroke by presence of sequels and history; and nephropathy by the urinary albumin excretion rate (>20 microg/min). Hypertension was defined by blood pressure (>140/90 mmHg) and/or use of antihypertensive drugs. Body mass index (BMI, kg/m2) and waist-to-hip ratio (WHR) were calculated.
RESULTS: CHD was present in 36% and PVD in 33% of the patients. Among the microvascular, 37% had nephropathy (12% with macroalbuminuria); 48% retinopathy (15% proliferative retinopathy). DSN was present in 36%. Seventy three percent of the patients presented arterial hypertension. Cholesterol levels were >200 mg/dl in 64% and BMI > 30 kg/m2 in 36%. Twenty two percent of patients were smokers and 21% ex-smokers.
CONCLUSION: Diabetic complications are frequent among out patients referring to general hospitals. Almost all patients presented at least one risk factor for cardiovascular disease, justifying the efforts for identification and adequate control.

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Year:  2004        PMID: 15499476     DOI: 10.1590/s0104-42302004000300031

Source DB:  PubMed          Journal:  Rev Assoc Med Bras (1992)        ISSN: 0104-4230            Impact factor:   1.209


  12 in total

1.  An Extended Minimal Physiologically Based Pharmacokinetic Model: Evaluation of Type II Diabetes Mellitus and Diabetic Nephropathy on Human IgG Pharmacokinetics in Rats.

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2.  Neuroprotective properties of aucubin in diabetic rats and diabetic encephalopathy rats.

Authors:  Hong Yu Xue; Ya Nan Lu; Xue Mei Fang; Yong Ping Xu; Gui Zhen Gao; Li Ji Jin
Journal:  Mol Biol Rep       Date:  2012-07-19       Impact factor: 2.316

3.  Effect of Type 2 Diabetes Mellitus and Diabetic Nephropathy on IgG Pharmacokinetics and Subcutaneous Bioavailability in the Rat.

Authors:  Gurkishan S Chadha; Marilyn E Morris
Journal:  AAPS J       Date:  2015-04-30       Impact factor: 4.009

4.  Prevalence and incidence of diabetic peripheral neuropathy in Latin America and the Caribbean: A systematic review and meta-analysis.

Authors:  Marlon Yovera-Aldana; Victor Velásquez-Rimachi; Andrely Huerta-Rosario; M D More-Yupanqui; Mariela Osores-Flores; Ricardo Espinoza; Fradis Gil-Olivares; César Quispe-Nolazco; Flor Quea-Vélez; Christian Morán-Mariños; Isabel Pinedo-Torres; Carlos Alva-Diaz; Kevin Pacheco-Barrios
Journal:  PLoS One       Date:  2021-05-13       Impact factor: 3.240

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Authors:  P Vejakama; A Thakkinstian; D Lertrattananon; A Ingsathit; C Ngarmukos; J Attia
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6.  Assessment of coronary heart diseases in diabetics in al-Madinah al-Munawarah.

Authors:  Omar Al-Nozha; Moaz Mojadadi; Mohamed Mosaad; Mohamed F El-Bab
Journal:  Int J Gen Med       Date:  2012-02-22

7.  Transcultural Diabetes Nutrition Algorithm: Brazilian Application.

Authors:  Fabio Moura; João Salles; Osama Hamdy; Walmir Coutinho; Deise Regina Baptista; Alexander Benchimol; Albert Marchetti; Refaat A Hegazi; Jeffrey I Mechanick
Journal:  Nutrients       Date:  2015-09-01       Impact factor: 5.717

8.  The effect of chinese herbal medicine on albuminuria levels in patients with diabetic nephropathy: a systematic review and meta-analysis.

Authors:  Ya Xiao; Yanyan Liu; Keqiang Yu; Lin Zhou; Jianlu Bi; Jingru Cheng; Fei Li; Ren Luo; Xiaoshan Zhao
Journal:  Evid Based Complement Alternat Med       Date:  2013-08-26       Impact factor: 2.629

Review 9.  Economic evaluations of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in type 2 diabetic nephropathy: a systematic review.

Authors:  Yunyu Huang; Qiyun Zhou; Flora M Haaijer-Ruskamp; Maarten J Postma
Journal:  BMC Nephrol       Date:  2014-01-15       Impact factor: 2.388

Review 10.  Epidemiology, management, complications and costs associated with type 2 diabetes in Brazil: a comprehensive literature review.

Authors:  Andréa D Bertoldi; Panos Kanavos; Giovanny V A França; André Carraro; Cesar Augusto Ovieda Tejada; Pedro C Hallal; Alessandra Ferrario; Maria Inês Schmidt
Journal:  Global Health       Date:  2013-12-03       Impact factor: 4.185

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