Literature DB >> 15499275

[Keratoconus: what happens with older patients?].

C Pobelle-Frasson1, S Velou, V Huslin, B Massicault, J Colin.   

Abstract

INTRODUCTION: Keratoconus is a degenerative corneal disease that is most often seen in young patients. The object of the present study was to analyze the demography of keratoconus patients. PATIENTS AND METHODS: We conducted a prospective study at Bordeaux University Hospital from January 2001 to September 2001. The study included all the consecutive patients with a diagnosis of keratoconus, detected previously or during the current examination. Inclusion criteria included evidence of unilateral or bilateral abnormal corneal steepening with videotopography.
RESULTS: We included 121 patients. The results showed a mean age of 33.4 years in males and 37.1 years in females. The number of patients older than 50 was low: 3 out of 83 (3.6%) males and 6 out of 38 (15.7%) females.
CONCLUSION: Two hypotheses on the low number of older patients can be suggested. 1) Keratoconus, which is a collagen disorder of the corneal stroma, may be associated with other undetected systemic diseases, which could induce premature death. Different studies have suggested a relationship between keratoconus and mitral valve prolapse. In this case, we can propose preventive treatment. 2) These patients, who have been informed of the nature and the therapeutical modalities of their disease, no longer consult at the hospital, but are followed by their local ophthalmologists.

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Mesh:

Year:  2004        PMID: 15499275     DOI: 10.1016/s0181-5512(04)96213-4

Source DB:  PubMed          Journal:  J Fr Ophtalmol        ISSN: 0181-5512            Impact factor:   0.818


  6 in total

1.  Corneal topographic changes in healthy siblings of patients with keratoconus.

Authors:  Mohammad Reza Besharati; Mohammad Reza Shoja; Masoud Reza Manaviat; Maryam Kheirandish; Maasome Zare Rad
Journal:  Int J Ophthalmol       Date:  2010-03-18       Impact factor: 1.779

2.  Keratoconus in the Medicare population.

Authors:  Sherman W Reeves; Leon B Ellwein; Terry Kim; Roberta Constantine; Paul P Lee
Journal:  Cornea       Date:  2009-01       Impact factor: 2.651

Review 3.  The genetic and environmental factors for keratoconus.

Authors:  Ariela Gordon-Shaag; Michel Millodot; Einat Shneor; Yutao Liu
Journal:  Biomed Res Int       Date:  2015-05-17       Impact factor: 3.411

4.  Effect of ageing on keratoconic corneas.

Authors:  Michel Millodot; Ilya Ortenberg; Karen Lahav-Yacouel; Shmuel Behrman
Journal:  J Optom       Date:  2015-07-02

5.  Keratoconus epidemiology: A review.

Authors:  José A P Gomes; Pablo F Rodrigues; Luiz L Lamazales
Journal:  Saudi J Ophthalmol       Date:  2022-07-11

Review 6.  Pathogenesis of Keratoconus: The intriguing therapeutic potential of Prolactin-inducible protein.

Authors:  Rabab Sharif; Sashia Bak-Nielsen; Jesper Hjortdal; Dimitrios Karamichos
Journal:  Prog Retin Eye Res       Date:  2018-07-13       Impact factor: 19.704

  6 in total

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