Literature DB >> 15498074

Life-threatening haematological disorders presenting with opthalmic manifestations.

David Z Wechsler, Thain S Tay, David L McKay.   

Abstract

Three cases are reported where life-threatening haematological disorders requiring urgent medical intervention presented initially to the ophthalmologist. Case one, chronic myeloid leukaemia, presented with bilateral leukaemic retinopathy and central retinal vein obstruction due to hyperviscosity. Case two, acute myeloid leukaemia, presented with bilateral haemorrhagic retinopathy. Case three, aplastic anaemia, presented with bilateral retinopathy due to anaemia and thrombocytopaenia resembling bilateral central retinal vein occlusion. In all three cases the presence of simultaneous bilateral retinal vascular involvement and white-centred haemorrhages suggested an underlying haematological disorder and differentiated them from typical retinal venous obstruction. Prompt identification of the underlying haematological disorder allows timely referral for potentially life-saving treatment.

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Year:  2004        PMID: 15498074     DOI: 10.1111/j.1442-9071.2004.00878.x

Source DB:  PubMed          Journal:  Clin Exp Ophthalmol        ISSN: 1442-6404            Impact factor:   4.207


  7 in total

1.  Bilateral vision loss as initial presentation of chronic myeloid leukemia in a young adult: A case report and review of the literature.

Authors:  Nathan J Brown; Erin A Kaya; Jonathan G Haymore; Lauren V Gioia
Journal:  Am J Ophthalmol Case Rep       Date:  2022-05-09

2.  Two red boats in the eye: subhyaloid haemorrhages in anaemic retinopathy secondary to idiopathic aplastic anaemia.

Authors:  Madhushmita Mahapatra; Subhakar Reddy; Sahil Goel; Mudit Tyagi
Journal:  BMJ Case Rep       Date:  2020-09-07

Review 3.  Ocular manifestations of idiopathic aplastic anemia: retrospective study and literature review.

Authors:  Ahmad M Mansour; Jong Wook Lee; Seung Ah Yahng; Kyu Seop Kim; Maha Shahin; Nelson Hamerschlak; Rubens N Belfort; Shree K Kurup
Journal:  Clin Ophthalmol       Date:  2014-04-17

4.  Bilateral Central Retinal Vein Occlusion as Presenting Feature of Chronic Myeloid Leukemia.

Authors:  Subina Narang; Panchmi Gupta; Anuj Sharma; Sunandan Sood; Anshu Palta; Shilpa Goyal
Journal:  Middle East Afr J Ophthalmol       Date:  2016 Jul-Sep

5.  Unilateral macular choroidal neovascularization-a rare manifestation in acute myelocytic leukemia: Case report.

Authors:  Xiaochun Yang; Jianbiao Xu; Jianhui Yang; Yikun Zhou; Yan Mei; Tonghua Yang; Yangmo Zhang
Journal:  Medicine (Baltimore)       Date:  2018-04       Impact factor: 1.889

Review 6.  Early Ophthalmological Manifestations of Acute Myeloid Leukemia: Current Perspectives.

Authors:  Nasrine Anais El Salloukh; Dany G Hage; Anna Z Bashshur; Wajiha Jurdi Kheir
Journal:  Clin Ophthalmol       Date:  2022-07-01

7.  Rare Presentation of Bilateral Central Retinal Vein Occlusion and Leukemic Retinopathy in a Young Adult Diagnosed with T-cell Acute Lymphoblastic Leukemia.

Authors:  Joshua H Uhr; Avrey Thau; Christine Chung; Xiao Chi Zhang
Journal:  Cureus       Date:  2020-01-15
  7 in total

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