| Literature DB >> 15496099 |
Alexander S Kiselyov1, Evgueni L Piatnitski, Jacqueline Doody.
Abstract
[reaction: see text] A convenient one-pot synthesis of 4-fluoroquinolinones that are active against KDR kinase is described. The mechanism of the reaction is believed to involve the formation of a quinone methide intermediate.Entities:
Year: 2004 PMID: 15496099 DOI: 10.1021/ol048257f
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005