| Literature DB >> 15495246 |
Ganesh C Kudva1, Kochurani Maliekel, John M Richart, Jacqueline R Batanian, Leonard E Grosso, Marcia Sokol-Anderson, Paul J Petruska.
Abstract
We report a 27-year-old man with HIV-1 infection who developed acute promyelocytic leukemia (APL) with a novel complex three-way chromosomal translocation t(15;16;17). Induction of remission and consolidation with all-trans-retinoic acid (ATRA)- and anthracycline-based chemotherapy was followed by maintenance therapy consisting of ATRA, 6-mercaptopurine (6-MP), and methotrexate (MTX). Highly active antiretroviral therapy (HAART) was continued with brief interruptions. He remains in complete remission 40 months after diagnosis.Entities:
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Year: 2004 PMID： 15495246 DOI： 10.1002/ajh.20192
Source DB: PubMed Journal: Am J Hematol ISSN： 0361-8609 Impact factor: 10.047