Literature DB >> 15493894

Formation of a stable 14-helix in short oligomers of furanoid cis-beta-sugar-amino acid.

Srivari Chandrasekhar1, Marepally Srinivasa Reddy, Bharatam Jagadeesh, Anabathula Prabhakar, Mallem H V Ramana Rao, Bulusu Jagannadh.   

Abstract

Oligomers of a new class of sugar amino acids (SAA) using a xylofuranoic acid has been shown to generate a robust 14-helix. The design involved the use of xylofuranose with a cis arrangement between the amine and carboxyl groups to promote the adoption of a 14-helix instead of a mixed 12/10-helix observed in a sugar oligomer using a ribofuranoic acid and beta-Ala. The observation of a stable right-handed 14-helix in a cis-SAA is unprecedented.

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Year:  2004        PMID： 15493894     DOI： 10.1021/ja0467667

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  6 in total

1.  Molecular dynamics simulation and conformational analysis of some catalytically active peptides.

Authors:  Bahareh Honarparvar; Adam A Skelton
Journal:  J Mol Model       Date:  2015-04-01       Impact factor: 1.810

2.  Differentiation of positional isomers of hybrid peptides containing repeats of β-nucleoside derived amino acid (β-Nda-) and L-amino acids by positive and negative ion electrospray ionization tandem mass spectrometry (ESI-MSn).

Authors:  B Raju; M Ramesh; R Srinivas; S Chandrasekhar; N Kiranmai; V U M Sarma
Journal:  J Am Soc Mass Spectrom       Date:  2011-02-08       Impact factor: 3.109

Review 3.  Synthesis and Applications of Carbohydrate-Based Organocatalysts.

Authors:  Elżbieta Wojaczyńska; Franz Steppeler; Dominika Iwan; Marie-Christine Scherrmann; Alberto Marra
Journal:  Molecules       Date:  2021-11-30       Impact factor: 4.411

4.  Synthesis and structural characterization of sialic acid-glutamic acid hybrid foldamers as conformational surrogates of alpha-2,8-linked polysialic acid.

Authors:  Jonel P Saludes; James B Ames; Jacquelyn Gervay-Hague
Journal:  J Am Chem Soc       Date:  2009-04-22       Impact factor: 15.419

5.  Synthesis of chimera oligopeptide including furanoid β-sugar amino acid derivatives with free OHs: mild but successful removal of the 1,2-O-isopropylidene from the building block.

Authors:  Kim Hoang Yen Duong; Viktória Goldschmidt Gőz; István Pintér; András Perczel
Journal:  Amino Acids       Date:  2021-02-09       Impact factor: 3.520

6.  Molecular architecture with carbohydrate functionalized β-peptides adopting 314-helical conformation.

Authors:  Nitin J Pawar; Navdeep S Sidhu; George M Sheldrick; Dilip D Dhavale; Ulf Diederichsen
Journal:  Beilstein J Org Chem       Date:  2014-04-28       Impact factor: 2.883
  6 in total

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