Tong Wu1, De-Yun Kong, Hui-Ting Li. 1. Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China. Tongwu8@hotmail.com
Abstract
AIM: To study the bioactive components from Helicia nilagirica. METHODS: Compounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence. RESULTS: Two compounds were isolated from the leaves of Helicia nilagirica. Compound 1 was elucidated as 1-O-3-D-glucopyranosyl-(2S,3S,4R,8Z)-2-[(2'R)-2'-hyd roxylignocenoyl-amino]-8-octadecene-1, 3, 4-triol. Compound 2 was an analogue of 1. CONCLUSION: The two compounds are new cerebrosides.
AIM: To study the bioactive components from Helicia nilagirica. METHODS: Compounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence. RESULTS: Two compounds were isolated from the leaves of Helicia nilagirica. Compound 1 was elucidated as 1-O-3-D-glucopyranosyl-(2S,3S,4R,8Z)-2-[(2'R)-2'-hyd roxylignocenoyl-amino]-8-octadecene-1, 3, 4-triol. Compound 2 was an analogue of 1. CONCLUSION: The two compounds are new cerebrosides.