Literature DB >> 15492892

On the genesis of myocardial ischemia.

K Sroka1.   

Abstract

About three quarters of myocardial ischemic events are triggered by the autonomic nervous system. The pathognomonic constellation is a combination of an almost complete withdrawal of tonic vagal activity with increased sympathetic activity. The reduction of tonic vagal activity, which is characteristic for ischemic heart disease, and the acute withdrawal of vagal drive preceding the onset of ischemia are not dependent on coronary artery disease. In this paper, the pathophysiological steps that lead from sympathetic-parasympathetic imbalance to myocardial ischemia shall be discussed. A considerable increase of aerobic glycolysis within the myocardium as a result of the autonomic imbalance is of special importance in this process.

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Year:  2004        PMID： 15492892     DOI： 10.1007/s00392-004-0137-6

Source DB:  PubMed          Journal:  Z Kardiol        ISSN： 0300-5860


  139 in total

1.  Reduced heart rate variability in ischemic heart disease is only partially caused by ischemia. An HRV study before and after PTCA.

Authors:  B Wennerblom; L Lurje; J Solem; H Tygesen; M Udén; R Vahisalo; A Hjalmarson
Journal:  Cardiology       Date:  2000       Impact factor: 1.869

2.  Beta-blocking effect of propafenone based on spectral analysis of heart rate variability.

Authors:  F Lombardi; D Torzillo; G Sandrone; L Dalla Vecchia; M L Finocchiaro; R Bernasconi; E Cappiello
Journal:  Am J Cardiol       Date:  1992-10-15       Impact factor: 2.778

Review 3.  Influence of myocardial ischemia and infarction on autonomic innervation of heart.

Authors:  D P Zipes
Journal:  Circulation       Date:  1990-10       Impact factor: 29.690

4.  Diurnal heart rate variability in healthy subjects: effects of aging and sex difference.

Authors:  Y Yamasaki; M Kodama; M Matsuhisa; M Kishimoto; H Ozaki; A Tani; N Ueda; Y Ishida; T Kamada
Journal:  Am J Physiol       Date:  1996-07

5.  Heart rate dynamics in patients with stable angina pectoris and utility of fractal and complexity measures.

Authors:  T H Mäkikallio; T Ristimäe; K E Airaksinen; C K Peng; A L Goldberger; H V Huikuri
Journal:  Am J Cardiol       Date:  1998-01-01       Impact factor: 2.778

6.  Oppositional effects of acetylcholine and isoproterenol on isometric tension and cyclic nucleotide concentrations in rabbit atria.

Authors:  W J George; L J Ignarro; R J Paddock; L White; P J Kadowitz
Journal:  J Cyclic Nucleotide Res       Date:  1975

7.  Heart rate variability before the occurrence of silent myocardial ischemia during ambulatory monitoring.

Authors:  Y Goseki; T Matsubara; N Takahashi; T Takeuchi; C Ibukiyama
Journal:  Am J Cardiol       Date:  1994-05-01       Impact factor: 2.778

8.  Circadian rhythms of frequency domain measures of heart rate variability in healthy subjects and patients with coronary artery disease. Effects of arousal and upright posture.

Authors:  H V Huikuri; M J Niemelä; S Ojala; A Rantala; M J Ikäheimo; K E Airaksinen
Journal:  Circulation       Date:  1994-07       Impact factor: 29.690

9.  Measurement of parasympathetic activity from 24-hour ambulatory electrocardiograms and its reproducibility and sensitivity in normal subjects, patients with symptomatic myocardial ischemia, and patients with diabetes mellitus.

Authors:  J Nolan; A D Flapan; N E Goodfield; R J Prescott; P Bloomfield; J M Neilson; D J Ewing
Journal:  Am J Cardiol       Date:  1996-01-15       Impact factor: 2.778

10.  Effects of enalapril on heart rate variability in patients with congestive heart failure.

Authors:  Y H Zhang; Y C Song; J Zhu; T H Hu; L L Wan
Journal:  Am J Cardiol       Date:  1995-11-15       Impact factor: 2.778
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  6 in total

1.  Modulation of rat parasympathetic cardiac ganglion phenotype and NGF synthesis by adrenergic nerves.

Authors:  Wohaib Hasan; Peter G Smith
Journal:  Auton Neurosci       Date:  2008-11-18       Impact factor: 3.145

2.  The role of muscarinic receptors in the beneficial effects of adenosine against myocardial reperfusion injury in rats.

Authors:  Lei Sun; Dong-Ling Li; Mei Zhao; Xi He; Xiao-Jiang Yu; Yi Miao; Hao Wang; Jun Ren; Wei-Jin Zang
Journal:  PLoS One       Date:  2011-11-04       Impact factor: 3.240

Review 3.  Autonomic cardiac innervation: development and adult plasticity.

Authors:  Wohaib Hasan
Journal:  Organogenesis       Date:  2013-05-14       Impact factor: 2.500

4.  Reduced Cell Excitability of Cardiac Postganglionic Parasympathetic Neurons Correlates With Myocardial Infarction-Induced Fatal Ventricular Arrhythmias in Type 2 Diabetes Mellitus.

Authors:  Wenfeng Hu; Dongze Zhang; Huiyin Tu; Yu-Long Li
Journal:  Front Neurosci       Date:  2021-08-18       Impact factor: 4.677

5.  Protection against ischemia-induced oxidative stress conferred by vagal stimulation in the rat heart: involvement of the AMPK-PKC pathway.

Authors:  Shan-Shan Kong; Jin-Jun Liu; Xiao-Jiang Yu; Yi Lu; Wei-Jin Zang
Journal:  Int J Mol Sci       Date:  2012-11-05       Impact factor: 5.923

6.  Reduced N-Type Ca2+ Channels in Atrioventricular Ganglion Neurons Are Involved in Ventricular Arrhythmogenesis.

Authors:  Dongze Zhang; Huiyin Tu; Liang Cao; Hong Zheng; Robert L Muelleman; Michael C Wadman; Yu-Long Li
Journal:  J Am Heart Assoc       Date:  2018-01-15       Impact factor: 5.501
  6 in total

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