Literature DB >> 15491306

Periodontal treatment of patients with Papillon-Lefèvre syndrome: a 3-year follow-up.

T Lundgren1, S Renvert.   

Abstract

BACKGROUND/AIM: Conventional mechanical periodontal treatment of Papillon-Lefevre syndrome (PLS) has often been reported to fail. This study describes the outcome of a non-surgical periodontal therapy including antimicrobial treatment of nine patients diagnosed with PLS. The patients originate from a total of 15 children and adolescents with PLS for which clinical characteristics are presented.
METHODS: Clinical examination including conventional periodontal measurements. Initial treatment including oral hygiene instruction, scaling and root planing and systemic amoxicillin-metronidazole therapy for 6 weeks. After that the patients were enrolled in a 3-month recall maintenance program. In addition to this mechanical supportive maintenance treatment, tetracycline was prescribed and used continuously for 1.5 years. RESULTS/
CONCLUSION: On five patients who were showing acceptable standard of oral hygiene and also compliance with the antibiotic medication, development of periodontitis on erupting teeth was prevented and disease activity on the previously periodontally involved teeth controlled during a 3-year period. Poor results of treatment were observed for three patients, all siblings. These patients failed to comply with the medication and also failed to improve their oral hygiene. (c) Blackwell Munksgaard, 2004

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Year:  2004        PMID: 15491306     DOI: 10.1111/j.1600-051X.2004.00591.x

Source DB:  PubMed          Journal:  J Clin Periodontol        ISSN: 0303-6979            Impact factor:   8.728


  9 in total

1.  A novel mutation in the cathepsin C gene in a Pakistani family with Papillon-Lefevre syndrome.

Authors:  M Kurban; T Cheng; M Wajid; M Kiuru; Y Shimomura; A M Christiano
Journal:  J Eur Acad Dermatol Venereol       Date:  2010-03-04       Impact factor: 6.166

2.  Long-Term Results after Placing Dental Implants in Patients with Papillon-Lefèvre Syndrome: Results 2.5-20 Years after Implant Insertion.

Authors:  Katrin Nickles; Mischa Krebs; Beate Schacher; Hari Petsos; Peter Eickholz
Journal:  J Clin Med       Date:  2022-04-26       Impact factor: 4.964

3.  Evidence for a founder mutation in the cathepsin C gene in three families with Papillon-Lefèvre syndrome.

Authors:  Mazen Kurban; Muhammad Wajid; Yutaka Shimomura; Ruba Bahhady; Abdul-Ghani Kibbi; Angela M Christiano
Journal:  Dermatology       Date:  2009-10-06       Impact factor: 5.366

4.  Identification of novel mutation in cathepsin C gene causing Papillon-Lefèvre Syndrome in Mexican patients.

Authors:  José G Romero-Quintana; Luis O Frías-Castro; Eliakym Arámbula-Meraz; Maribel Aguilar-Medina; Jesús E Dueñas-Arias; Jesús D Melchor-Soto; José G Romero-Navarro; Rosalío Ramos-Payán
Journal:  BMC Med Genet       Date:  2013-01-11       Impact factor: 2.103

5.  Papillon-Lefevre syndrome: A case report of 2 affected siblings.

Authors:  Anupriya Sharma; Gurpreet Kaur; Ashish Sharma
Journal:  J Indian Soc Periodontol       Date:  2013-05

6.  Papillon-lefevre syndrome: Case series and review of literature.

Authors:  Margi V Bhavsar; Nilam A Brahmbhatt; Vishal N Sahayata; Neeta V Bhavsar
Journal:  J Indian Soc Periodontol       Date:  2013-11

Review 7.  CTSC and Papillon-Lefèvre syndrome: detection of recurrent mutations in Hungarian patients, a review of published variants and database update.

Authors:  Nikoletta Nagy; Péter Vályi; Zsanett Csoma; Adrienn Sulák; Kornélia Tripolszki; Katalin Farkas; Ekaterine Paschali; Ferenc Papp; Lola Tóth; Beáta Fábos; Lajos Kemény; Katalin Nagy; Márta Széll
Journal:  Mol Genet Genomic Med       Date:  2014-02-11       Impact factor: 2.183

8.  Whole-exome sequencing reveals a recurrent mutation in the cathepsin C gene that causes Papillon-Lefevre syndrome in a Saudi family.

Authors:  Yaser Mohammad Alkhiary; Musharraf Jelani; Mona Mohammad Almramhi; Hussein Sheikh Ali Mohamoud; Rayan Al-Rehaili; Hams Saeed Al-Zahrani; Rehab Serafi; Huanming Yang; Jumana Yousuf Al-Aama
Journal:  Saudi J Biol Sci       Date:  2015-06-16       Impact factor: 4.219

9.  A novel mutation in the cathepsin C (CTSC) gene in Iranian family with Papillon-Lefevre syndrome.

Authors:  Mahmoud Ghanei; Mohammad R Abbaszadegan; Mohammad M Forghanifard; Azadeh Aarabi; Hamidreza Arab
Journal:  Clin Exp Dent Res       Date:  2021-02-14
  9 in total

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